Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DV131_RS05030 Genome accession   NZ_CP031246
Coordinates   921138..921770 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain M26368     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 916138..926770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS05005 mvaD 916415..917368 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  DV131_RS05010 - 917355..918362 (+) 1008 WP_061366143.1 phosphomevalonate kinase -
  DV131_RS05015 fni 918346..919356 (+) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  DV131_RS05020 liaF 919434..920132 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  DV131_RS05025 - 920129..921124 (+) 996 WP_000743680.1 sensor histidine kinase -
  DV131_RS05030 vraR 921138..921770 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  DV131_RS11815 - 921846..922540 (+) 695 Protein_911 DNA alkylation repair protein -
  DV131_RS05050 - 922690..922929 (+) 240 WP_000754501.1 hypothetical protein -
  DV131_RS05055 cbpG 923010..923600 (+) 591 Protein_913 choline-binding protein CbpG -
  DV131_RS05060 - 923956..924294 (+) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  DV131_RS05065 tig 924455..925738 (+) 1284 WP_000116465.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=263154 DV131_RS05030 WP_000698434.1 921138..921770(+) (vraR) [Streptococcus pneumoniae strain M26368]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=263154 DV131_RS05030 WP_000698434.1 921138..921770(+) (vraR) [Streptococcus pneumoniae strain M26368]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41