Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CRH08_RS09250 Genome accession   NZ_CP025419
Coordinates   1779755..1780444 (-) Length   229 a.a.
NCBI ID   WP_112493947.1    Uniprot ID   -
Organism   Streptococcus suis strain SH0104     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1774755..1785444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRH08_RS09225 - 1775225..1775938 (-) 714 WP_009910601.1 NADPH-dependent oxidoreductase -
  CRH08_RS09230 dnaI 1775935..1776834 (-) 900 WP_002938337.1 primosomal protein DnaI -
  CRH08_RS09235 - 1776834..1777985 (-) 1152 WP_009910602.1 replication initiation and membrane attachment protein -
  CRH08_RS09240 nrdR 1777972..1778463 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  CRH08_RS09245 - 1778535..1779665 (-) 1131 WP_013730514.1 AI-2E family transporter -
  CRH08_RS09250 covR 1779755..1780444 (-) 690 WP_112493947.1 winged helix-turn-helix domain-containing protein Regulator
  CRH08_RS09255 gndA 1780526..1781953 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  CRH08_RS09260 - 1782050..1782589 (-) 540 WP_013730515.1 DUF177 domain-containing protein -
  CRH08_RS09265 trxB 1782599..1783516 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  CRH08_RS09270 - 1783530..1783754 (-) 225 WP_002936682.1 DUF4059 family protein -
  CRH08_RS09275 - 1783772..1785115 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26251.14 Da        Isoelectric Point: 5.1834

>NTDB_id=261127 CRH08_RS09250 WP_112493947.1 1779755..1780444(-) (covR) [Streptococcus suis strain SH0104]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAYETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=261127 CRH08_RS09250 WP_112493947.1 1779755..1780444(-) (covR) [Streptococcus suis strain SH0104]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCATATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment