Detailed information NTG0261100

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: CRH08_RS00830
• Genome accession: NZ_CP025419
• Coordinates: 126498..127451 (+)
• Length: 317 a.a.
• NCBI ID: WP_024409299.1
• Uniprot ID: A0A7Y6VE95
• Organism: Streptococcus suis strain SH0104
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 121498..132451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRH08_RS00790	-	121761..122711 (-)	951	WP_002936565.1	S66 peptidase family protein	-
CRH08_RS00795	comYA	122797..123747 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
CRH08_RS00800	comYB	123659..124696 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
CRH08_RS00805	comYC	124698..124979 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
CRH08_RS00810	comGD	124960..125367 (+)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
CRH08_RS00815	comYE	125339..125632 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
CRH08_RS00820	comGF/cglF	125619..126053 (+)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
CRH08_RS00825	comGG	126031..126441 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
CRH08_RS00830	comYH	126498..127451 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
CRH08_RS00835	-	127501..128688 (+)	1188	WP_013730078.1	acetate kinase	-
CRH08_RS00845	-	129003..129599 (+)	597	WP_009909104.1	folate family ECF transporter S component	-
CRH08_RS00850	-	129610..130866 (+)	1257	WP_013730079.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
CRH08_RS00855	pepA	130912..131973 (-)	1062	WP_002936538.1	glutamyl aminopeptidase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35807.97 Da
• Isoelectric Point: 4.4571

>NTDB_id=261100 CRH08_RS00830 WP_024409299.1 126498..127451(+) (comYH) [Streptococcus suis strain SH0104]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVANQHEMDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLMPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide

• Length: 954 bp

>NTDB_id=261100 CRH08_RS00830 WP_024409299.1 126498..127451(+) (comYH) [Streptococcus suis strain SH0104]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTAATCAGCATGAGATGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAACCCATGCAGTACAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGATGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTGAAATATCTGGAAAAAGATGGCTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTGCCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCGTTGACGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-283)

3D structure

• AlphaFold DB: A0A7Y6VE95

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	60.759	99.685	0.606
comYH	Streptococcus mutans UA159	60.443	99.685	0.603