Detailed information NTG0260878

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CYD28_RS04985
• Genome accession: NZ_CP025396
• Coordinates: 1037506..1038552 (+)
• Length: 348 a.a.
• NCBI ID: WP_059767274.1
• Uniprot ID: -
• Organism: Staphylococcus haemolyticus strain B
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1032506..1043552

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CYD28_RS04960 (CYD28_04960)	map	1033366..1034118 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
CYD28_RS04965 (CYD28_04965)	-	1034243..1035100 (-)	858	WP_011275370.1	SDR family oxidoreductase	-
CYD28_RS04970 (CYD28_04970)	-	1035172..1036184 (-)	1013	Protein_987	HoxN/HupN/NixA family nickel/cobalt transporter	-
CYD28_RS04975 (CYD28_04975)	-	1036397..1036783 (+)	387	WP_011275373.1	hypothetical protein	-
CYD28_RS04980 (CYD28_04980)	liaF	1036808..1037509 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
CYD28_RS04985 (CYD28_04985)	vraS	1037506..1038552 (+)	1047	WP_059767274.1	sensor histidine kinase	Regulator
CYD28_RS04990 (CYD28_04990)	vraR	1038542..1039171 (+)	630	WP_011275376.1	two-component system response regulator VraR	Regulator
CYD28_RS04995 (CYD28_04995)	-	1039235..1040446 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
CYD28_RS05000 (CYD28_05000)	-	1040643..1040927 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
CYD28_RS05005 (CYD28_05005)	-	1040933..1041397 (-)	465	WP_011275379.1	low molecular weight protein-tyrosine-phosphatase	-
CYD28_RS05010 (CYD28_05010)	-	1041539..1041748 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
CYD28_RS05015 (CYD28_05015)	-	1041762..1043009 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40193.61 Da
• Isoelectric Point: 6.0550

>NTDB_id=260878 CYD28_RS04985 WP_059767274.1 1037506..1038552(+) (vraS) [Staphylococcus haemolyticus strain B]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=260878 CYD28_RS04985 WP_059767274.1 1037506..1038552(+) (vraS) [Staphylococcus haemolyticus strain B]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAATCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGGGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.931	99.713	0.917