Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SAO46_RS08175 Genome accession   NZ_CP025395
Coordinates   1641974..1642660 (-) Length   228 a.a.
NCBI ID   WP_078064899.1    Uniprot ID   -
Organism   Staphylococcus aureus O46     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1636974..1647660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAO46_RS08155 (SAO46_01496) rpsT 1637888..1638139 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  SAO46_RS08160 (SAO46_01497) holA 1638184..1639158 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  SAO46_RS08165 (SAO46_01498) comEC 1639215..1641416 (-) 2202 WP_025174647.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SAO46_RS08170 (SAO46_01499) - 1641421..1641882 (-) 462 WP_000439693.1 ComE operon protein 2 -
  SAO46_RS08175 (SAO46_01500) comEA 1641974..1642660 (-) 687 WP_078064899.1 ComEA family DNA-binding protein Machinery gene
  SAO46_RS08180 (SAO46_01501) - 1642700..1643416 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  SAO46_RS08185 (SAO46_01502) rsfS 1643419..1643772 (-) 354 WP_001088020.1 ribosome silencing factor -
  SAO46_RS08190 (SAO46_01503) yqeK 1643773..1644357 (-) 585 WP_001019325.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SAO46_RS08195 (SAO46_01504) nadD 1644347..1644916 (-) 570 WP_000725161.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  SAO46_RS08200 (SAO46_01505) yhbY 1644919..1645209 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  SAO46_RS08205 (SAO46_01506) aroE 1645213..1646019 (-) 807 WP_000666751.1 shikimate dehydrogenase -
  SAO46_RS08210 (SAO46_01507) yqeH 1646033..1647133 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25873.67 Da        Isoelectric Point: 9.7956

>NTDB_id=260850 SAO46_RS08175 WP_078064899.1 1641974..1642660(-) (comEA) [Staphylococcus aureus O46]
MVLLYQFLLRYKDFLTQWKLYIISVVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSEISSLSKLEDVQVKDRDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVDPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=260850 SAO46_RS08175 WP_078064899.1 1641974..1642660(-) (comEA) [Staphylococcus aureus O46]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGTTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAATTAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATAGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGACCCACAAATTGGAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.916

99.561

0.965
  comEA Staphylococcus aureus N315

96.916

99.561

0.965

Multiple sequence alignment