Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPD_RS05545 Genome accession   NC_008533
Coordinates   1057873..1058337 (-) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae D39     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1052873..1063337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPD_RS05525 (SPD_1028) - 1053824..1054792 (-) 969 WP_000105362.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  SPD_RS05530 (SPD_1029) pdrM 1054946..1056307 (-) 1362 WP_000278532.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  SPD_RS05535 - 1056318..1056578 (-) 261 WP_001105925.1 hypothetical protein -
  SPD_RS05540 (SPD_1030) - 1056592..1057860 (-) 1269 WP_000924481.1 dihydroorotase -
  SPD_RS05545 (SPD_1031) mutX 1057873..1058337 (-) 465 WP_001135782.1 NUDIX hydrolase Machinery gene
  SPD_RS05550 (SPD_1032) - 1058347..1059000 (-) 654 WP_000401328.1 uracil-DNA glycosylase -
  SPD_RS05555 (SPD_1033) - 1059136..1059783 (-) 648 WP_001824648.1 hypothetical protein -
  SPD_RS05560 (SPD_1034) - 1059797..1060510 (-) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  SPD_RS05565 dhaM 1060968..1061348 (-) 381 Protein_1052 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  SPD_RS12005 - 1061348..1061422 (-) 75 Protein_1053 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=26007 SPD_RS05545 WP_001135782.1 1057873..1058337(-) (mutX) [Streptococcus pneumoniae D39]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=26007 SPD_RS05545 WP_001135782.1 1057873..1058337(-) (mutX) [Streptococcus pneumoniae D39]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACCTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1

Multiple sequence alignment