Detailed information NTG0260002

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CXP43_RS18615
• Genome accession: NZ_CP025308
• Coordinates: 3696577..3697740 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain Lzh-a42
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3691577..3702740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CXP43_RS18585 (CXP43_18585)	-	3691842..3692261 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
CXP43_RS18590 (CXP43_18590)	comFC	3692335..3693024 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
CXP43_RS18595 (CXP43_18595)	-	3693030..3693314 (-)	285	WP_014419011.1	late competence development ComFB family protein	-
CXP43_RS18600 (CXP43_18600)	comFA	3693372..3694757 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
CXP43_RS18605 (CXP43_18605)	-	3694865..3695713 (-)	849	WP_003151387.1	DegV family protein	-
CXP43_RS18610 (CXP43_18610)	degU	3695811..3696500 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CXP43_RS18615 (CXP43_18615)	degS	3696577..3697740 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CXP43_RS18620 (CXP43_18620)	-	3697963..3698610 (+)	648	WP_007614107.1	YigZ family protein	-
CXP43_RS18625 (CXP43_18625)	-	3698615..3699829 (+)	1215	WP_014419013.1	LCP family protein	-
CXP43_RS18630 (CXP43_18630)	-	3699919..3700995 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CXP43_RS18635 (CXP43_18635)	tuaH	3701128..3702324 (-)	1197	WP_014419014.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=260002 CXP43_RS18615 WP_007407484.1 3696577..3697740(-) (degS) [Bacillus velezensis strain Lzh-a42]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=260002 CXP43_RS18615 WP_007407484.1 3696577..3697740(-) (degS) [Bacillus velezensis strain Lzh-a42]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951