Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   CXL14_RS08330 Genome accession   NZ_CP025258
Coordinates   1645935..1646579 (+) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus sp. SJ-10     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1640935..1651579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXL14_RS08300 - 1641351..1641692 (-) 342 WP_014418765.1 hypothetical protein -
  CXL14_RS08310 degQ 1642158..1642298 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  CXL14_RS08315 - 1642429..1643355 (+) 927 WP_014721741.1 polyprenyl synthetase family protein -
  CXL14_RS08320 comX 1643355..1643525 (+) 171 WP_032863917.1 competence pheromone ComX -
  CXL14_RS08325 comP 1643503..1645854 (+) 2352 WP_269800792.1 histidine kinase Regulator
  CXL14_RS08330 comA 1645935..1646579 (+) 645 WP_014418762.1 response regulator transcription factor Regulator
  CXL14_RS08335 - 1646601..1646984 (+) 384 WP_014418761.1 hotdog fold thioesterase -
  CXL14_RS08340 mnhG 1647024..1647398 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  CXL14_RS08345 - 1647382..1647666 (-) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  CXL14_RS08350 - 1647666..1648142 (-) 477 WP_014418760.1 Na+/H+ antiporter subunit E -
  CXL14_RS08355 - 1648148..1649629 (-) 1482 WP_032863920.1 Na+/H+ antiporter subunit D -
  CXL14_RS08360 - 1649622..1649963 (-) 342 WP_014418758.1 Na(+)/H(+) antiporter subunit C -
  CXL14_RS08365 - 1649963..1650394 (-) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=259544 CXL14_RS08330 WP_014418762.1 1645935..1646579(+) (comA) [Bacillus sp. SJ-10]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=259544 CXL14_RS08330 WP_014418762.1 1645935..1646579(+) (comA) [Bacillus sp. SJ-10]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTTCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGTTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment