Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPAG1_RS00120 Genome accession   NC_008086
Coordinates   15556..17919 (+) Length   787 a.a.
NCBI ID   WP_000890493.1    Uniprot ID   -
Organism   Helicobacter pylori HPAG1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 10556..22919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPAG1_RS00090 (HPAG1_0011) groES 10579..10935 (-) 357 WP_000671934.1 co-chaperone GroES -
  HPAG1_RS00095 (HPAG1_0012) dnaG 11222..12901 (+) 1680 WP_000601589.1 DNA primase -
  HPAG1_RS00100 (HPAG1_0013) - 12898..13950 (+) 1053 WP_000721204.1 MnmA/TRMU family protein -
  HPAG1_RS00105 (HPAG1_0014) - 14039..14865 (+) 827 Protein_13 DUF5718 family protein -
  HPAG1_RS00110 (HPAG1_0015) comB2 15010..15291 (+) 282 WP_001279601.1 TrbC/VirB2 family protein Machinery gene
  HPAG1_RS00115 (HPAG1_0016) comB3 15291..15554 (+) 264 WP_000584973.1 hypothetical protein Machinery gene
  HPAG1_RS00120 (HPAG1_0017) comB4 15556..17919 (+) 2364 WP_000890493.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPAG1_RS00125 (HPAG1_0018) - 18221..19561 (+) 1341 WP_041200025.1 COG3014 family protein -
  HPAG1_RS00130 (HPAG1_0019) cheV1 19657..20622 (+) 966 WP_000785504.1 chemotaxis protein CheV1 -
  HPAG1_RS00135 (HPAG1_0020) nspC 20619..21836 (+) 1218 WP_000760838.1 carboxynorspermidine decarboxylase -
  HPAG1_RS00140 (HPAG1_0021) lpxE 21846..22412 (-) 567 WP_000819524.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90372.99 Da        Isoelectric Point: 8.9625

>NTDB_id=25952 HPAG1_RS00120 WP_000890493.1 15556..17919(+) (comB4) [Helicobacter pylori HPAG1]
MLEKLLNAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQADSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGQSFSINPFYLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAVFSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDALNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=25952 HPAG1_RS00120 WP_000890493.1 15556..17919(+) (comB4) [Helicobacter pylori HPAG1]
ATGTTAGAAAAGCTTTTGAACGCTATCAAACAAAAGGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCCAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTCTTGCTCACTAAAAACGAAAACTTAGTGGGTATTCTTC
GTTTAGAAGGGGTTAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTCTTCACCGAGCGCCAGATGGCGTTGGAT
TCTTTAGAAAAAGTTGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAGCTGACTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAGGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ATTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGACATCCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGTTTTAATCAAAAAACCTACAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAAACGCC
ACTAGATATTATCTTTTCCATAGAACCTATGAGCGTGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTTGTTAAAAACGAGCTGCTAGAATACCAAGAACTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGCTTTTTAACTTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTTCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAATCATAGGGGCTACTGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGTTG
TATTCTTTCACCAAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTATTTAGAGCCTAA
TTTACAGAATCTAGAATTTTTGCAATCCTTCTTTTTGAGCATGCTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGGTTTTTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCCTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTAAGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCACTCAACTCCAACGCTTTTTTAAATGTGATAAACCTGGACACCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATTTTAGAAGAATCCAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAATTAAGTGGGGTTAAAAACGCTCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAATTCTAACATGATTGATGT
GAGTTTGGAAAGTTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCAAAAGAGTGGCGTGAAAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.459

100

0.975

Multiple sequence alignment