Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DP112_RS02170 Genome accession   NZ_CP030125
Coordinates   417111..417752 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain HA1003     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 412111..422752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS02150 (DP112_02150) - 412411..413148 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DP112_RS02155 (DP112_02155) stkP 413148..415142 (+) 1995 WP_114866239.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DP112_RS02160 (DP112_02160) liaF 415431..416126 (+) 696 WP_105135492.1 cell wall-active antibiotics response protein LiaF -
  DP112_RS02165 (DP112_02165) - 416123..417139 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DP112_RS02170 (DP112_02170) vraR 417111..417752 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  DP112_RS02175 (DP112_02175) - 417802..419202 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  DP112_RS02180 (DP112_02180) - 419204..419575 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DP112_RS02185 (DP112_02185) cysK 419601..420527 (-) 927 WP_029172049.1 cysteine synthase A -
  DP112_RS02190 (DP112_02190) - 420617..421249 (-) 633 WP_161947046.1 YigZ family protein -
  DP112_RS02195 (DP112_02195) comFA/cflA 421306..422598 (+) 1293 WP_114866240.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=258928 DP112_RS02170 WP_002937025.1 417111..417752(+) (vraR) [Streptococcus suis strain HA1003]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=258928 DP112_RS02170 WP_002937025.1 417111..417752(+) (vraR) [Streptococcus suis strain HA1003]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGTGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCTTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTGAGCGACCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413