Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DP112_RS00360 Genome accession   NZ_CP030125
Coordinates   59686..61623 (+) Length   645 a.a.
NCBI ID   WP_029172056.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 54686..66623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS00335 (DP112_00335) - 54790..55413 (+) 624 WP_114866090.1 HAD-IA family hydrolase -
  DP112_RS00340 (DP112_00340) comR 55518..56417 (+) 900 WP_114866091.1 helix-turn-helix domain-containing protein Regulator
  DP112_RS00345 (DP112_00345) - 56634..57854 (+) 1221 WP_114866092.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  DP112_RS00355 (DP112_00355) - 58045..59568 (+) 1524 WP_114866093.1 quinol oxidase -
  DP112_RS00360 (DP112_00360) hexB 59686..61623 (+) 1938 WP_029172056.1 DNA mismatch repair endonuclease MutL Machinery gene
  DP112_RS00365 (DP112_00365) ruvA 61662..62252 (+) 591 WP_114866094.1 Holliday junction branch migration protein RuvA Machinery gene
  DP112_RS00370 (DP112_00370) - 62493..63062 (+) 570 WP_114866095.1 DNA-3-methyladenine glycosylase I -
  DP112_RS00375 (DP112_00375) cinA 63099..64280 (+) 1182 WP_114866096.1 competence/damage-inducible protein A Machinery gene
  DP112_RS00380 (DP112_00380) recA 64332..65483 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  DP112_RS00385 (DP112_00385) spx 65719..66117 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DP112_RS00390 (DP112_00390) - 66217..66483 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72883.08 Da        Isoelectric Point: 5.1710

>NTDB_id=258903 DP112_RS00360 WP_029172056.1 59686..61623(+) (hexB) [Streptococcus suis strain HA1003]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMVIETATADSTHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLKEPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALNLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=258903 DP112_RS00360 WP_029172056.1 59686..61623(+) (hexB) [Streptococcus suis strain HA1003]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGGTCATTGAGACAGCTACAGCAGACTCTACACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCGTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATTTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTATGGTAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATTGACCCTTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAAAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCGACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGTAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TATCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTAACCTTGTCCACAAAATGGATGCTCTTCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTTTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAATTGCCCGCACGGTC
GCCCTGTCTTAGTGCATTTTAGCAAGTCGGACATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGT
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732