Detailed information NTG0258014

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: A7J09_RS11910
• Genome accession: NZ_CP030015
• Coordinates: 2482730..2485270 (-)
• Length: 846 a.a.
• NCBI ID: WP_053861554.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2812
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2477730..2490270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J09_RS11885 (A7J09_12120)	-	2478888..2479631 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
A7J09_RS11890 (A7J09_12125)	-	2479631..2480434 (-)	804	WP_014637221.1	amino acid ABC transporter permease	-
A7J09_RS11895 (A7J09_12130)	-	2480620..2481471 (-)	852	WP_013730662.1	amino acid ABC transporter substrate-binding protein	-
A7J09_RS11900 (A7J09_12135)	-	2481504..2482190 (-)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
A7J09_RS11905 (A7J09_12140)	-	2482304..2482477 (-)	174	WP_009910995.1	hypothetical protein	-
A7J09_RS11910 (A7J09_12150)	hexA	2482730..2485270 (-)	2541	WP_053861554.1	DNA mismatch repair protein MutS	Machinery gene
A7J09_RS11915 (A7J09_12155)	argR	2485285..2485725 (-)	441	WP_032512697.1	arginine repressor	-
A7J09_RS11920 (A7J09_12160)	argS	2485832..2487520 (+)	1689	WP_029174610.1	arginine--tRNA ligase	-
A7J09_RS11925 (A7J09_12165)	-	2487700..2488614 (+)	915	WP_029752992.1	SH3 domain-containing protein	-
A7J09_RS11930 (A7J09_12170)	-	2488668..2489192 (-)	525	WP_024394551.1	membrane protein	-
A7J09_RS11935 (A7J09_12175)	-	2489304..2489489 (+)	186	WP_053861553.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95093.60 Da
• Isoelectric Point: 4.8806

>NTDB_id=258014 A7J09_RS11910 WP_053861554.1 2482730..2485270(-) (hexA) [Streptococcus suis strain ISU2812]
MATEKISPGMQQYLDIKANYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLDNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSSNLEYEIFMRIRQEVEKYISRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTINRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDQSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPAKPAPSVV
AEPSGQIDLFADTPSHPVLKELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=258014 A7J09_RS11910 WP_053861554.1 2482730..2485270(-) (hexA) [Streptococcus suis strain ISU2812]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCAAACTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GTAATAAGAATGCGGAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAACTGGGGCATAAGGTCGCTATAGCTGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTGGT
GCAGGTCATCACGCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGAGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCTAATCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGACGTCCAGCTGATTGACAATTCGCTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCATTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGATCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCATTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTACAGGTCTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGAGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATCCCAGAACTGCATGCTCTGATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACTATCACAGATGGGAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCCGGTATCAACAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGACAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAATTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGCGACAAGTC
GTCTAACTTGGAGTACGAGATTTTCATGCGGATTCGTCAAGAGGTTGAAAAATATATCAGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCGACCATCGATGTTTTGCAGGCTTTTGCAGTTGTGGCAGAGCAGCAACATTTGGTTTGTCCACGCTTCACA
GATCAAAGAGAACTGACCATTAACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCAGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATCTTCACCCGTATCGGTGCGGCAGATGATCTAGTCAGCGGTCAATCGACCTTCATGGTGGAGATGATGGAGGCCAACAA
GGCAGTCCGCTTGGCGACAGACCAGTCCCTAATTCTCTTTGATGAGCTGGGTCGGGGAACAGCCACTTACGACGGCATGG
CTCTGGCCCAGTCTATCATCGAGTATATCCACGACAAGATTGGAGCCAAGACCCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTGTCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCACAAGGCCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGCTAT
TGCAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAGCAAAACCAGCTCCATCAGTGGTG
GCAGAACCGTCTGGTCAAATCGACCTCTTTGCAGACACACCTTCTCACCCAGTCCTCAAAGAATTAGAAAAACTGGACAT
CTACAATATGACCCCAATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.641	100	0.736
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383