Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   RMET_RS05245 Genome accession   NC_007973
Coordinates   1133224..1135779 (+) Length   851 a.a.
NCBI ID   WP_011515834.1    Uniprot ID   Q1LPJ7
Organism   Cupriavidus metallidurans CH34     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1128224..1140779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMET_RS05225 (Rmet_1039) - 1129000..1130118 (-) 1119 WP_011515830.1 hypothetical protein -
  RMET_RS05230 (Rmet_1040) - 1130222..1131472 (+) 1251 WP_011515831.1 lipoprotein-releasing ABC transporter permease subunit -
  RMET_RS05235 (Rmet_1041) - 1131465..1132214 (+) 750 WP_011515832.1 ABC transporter ATP-binding protein -
  RMET_RS05240 (Rmet_1042) - 1132266..1133093 (+) 828 WP_011515833.1 TatD family hydrolase -
  RMET_RS05245 (Rmet_1043) comA 1133224..1135779 (+) 2556 WP_011515834.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RMET_RS05250 (Rmet_1044) - 1135746..1136762 (-) 1017 WP_011515835.1 MurR/RpiR family transcriptional regulator -
  RMET_RS05255 (Rmet_1045) edd 1137061..1138950 (+) 1890 WP_011515836.1 phosphogluconate dehydratase -
  RMET_RS05260 (Rmet_1046) - 1139122..1139637 (+) 516 WP_011515837.1 gluconokinase -

Sequence

Protein


Download         Length: 851 a.a.        Molecular weight: 91525.25 Da        Isoelectric Point: 10.5926

>NTDB_id=25783 RMET_RS05245 WP_011515834.1 1133224..1135779(+) (comA) [Cupriavidus metallidurans CH34]
MRAVLLAFVVGCWWLQQQAALPGPWDWVVWGCFALVGLFGVWGVRGRGARWVVWARWLVSLSIAAIVGLGWSAWRADMRL
GAWLDPSLAGRDQIIDGVVSGLPDAAPHGTRFLFTVESGASGGVAMGDRHAGVAPLSTAPLPPRVLLTWRDPPEVLQPGQ
RHRLTVRLRRPRGLANPHGFDYGYWLLAEGIGATGYVRHGQLLNRDAAMPLSIRITQWRAGLRDRLWAALPSDAQYRAVL
VALVIGDQRGIGQADWDVFRRTGISHLVSISGLHITMISGAVAALAGMLWRHSFGIGRKLRRPLPLIWPAQKVAMVVAVQ
TALGYGLIAGMQIPALRTVSMLMVAAVALWSGRMPPPTVVLAWAAGIAVAIDPWAVMSPGFWLSFGAVAVIFLGARGDGS
GDGGAVEERQADPKSCVSRCVSRWVSRIGGVAAEAARTQWSVTIGLVPLTLLLFGQVSVVSVFANAVAIPVVSLLVTPLA
LAGAVLPPGWAAPLLWIAHKALEWLVGGLAWLAAPAWAVWEAAHPGPVATGLALAGVYVLLIPRPSDAKGARRVQIVPRW
LGVLLMVPMLSAGPEPVEEGEMRVTALDVGQGAAVLVETRRHVLLYDTGPSYVSGASAGGQVIVPYLRATGVRHLDMLMV
SHEHDDHAGGVEAVLQAVPVARGLTAEGPGNKPLPGLLQGRAWQPCLDGVAWRWDGVDFEVLHPTEEGLARQRLSANARS
CVLRVATAQRSLLLTGDIGVSEERRLIDSELGERLRADFLLVPHHGSGTSSHAAFLRAVQPEVAVFQLGFANRHRHPRED
VWRRYARAGAARYRTDETGAVSIVTGGGDYVVTSFRQQQRRYWRDAPPAPR

Nucleotide


Download         Length: 2556 bp        

>NTDB_id=25783 RMET_RS05245 WP_011515834.1 1133224..1135779(+) (comA) [Cupriavidus metallidurans CH34]
ATGCGTGCAGTGCTGCTCGCGTTCGTGGTGGGCTGCTGGTGGTTGCAGCAGCAGGCGGCACTGCCGGGGCCATGGGATTG
GGTCGTTTGGGGGTGTTTTGCGCTGGTTGGACTGTTTGGGGTTTGGGGGGTGCGCGGGCGTGGGGCGCGGTGGGTAGTCT
GGGCTCGATGGTTGGTGAGCCTGTCAATCGCGGCAATCGTGGGGTTGGGTTGGTCGGCGTGGCGGGCGGACATGCGGCTC
GGTGCCTGGCTGGACCCGTCACTGGCAGGGCGTGATCAAATCATCGACGGTGTTGTCAGCGGATTGCCGGACGCGGCCCC
GCACGGCACGCGGTTCCTGTTCACGGTGGAGAGCGGGGCGTCGGGTGGCGTGGCGATGGGAGATCGCCACGCAGGGGTGG
CGCCACTGTCAACAGCGCCATTGCCGCCCAGGGTATTGCTGACGTGGCGAGATCCGCCGGAGGTGCTGCAGCCCGGCCAG
CGCCATCGGTTGACGGTCCGTCTGCGCAGACCGCGCGGTCTCGCGAATCCGCATGGTTTCGACTATGGCTACTGGCTGCT
TGCCGAAGGCATCGGGGCGACGGGCTATGTACGCCACGGTCAGTTGCTGAATCGTGATGCCGCGATGCCGTTGTCGATCC
GGATCACGCAGTGGCGGGCCGGATTGCGTGACCGCTTGTGGGCGGCGTTGCCATCCGATGCGCAATACCGGGCAGTGCTC
GTCGCGCTGGTGATCGGTGATCAGCGGGGCATTGGGCAGGCGGACTGGGATGTGTTCCGGCGCACCGGCATCTCCCATCT
GGTCAGCATCTCCGGGCTGCACATCACGATGATATCGGGGGCAGTTGCGGCGCTCGCGGGCATGCTTTGGCGCCATTCGT
TCGGCATCGGACGCAAGCTCCGGCGGCCGCTGCCGCTGATCTGGCCCGCGCAGAAGGTGGCGATGGTGGTAGCGGTGCAG
ACGGCGCTCGGCTACGGGCTGATTGCGGGCATGCAGATCCCGGCGCTGCGCACGGTATCGATGCTGATGGTCGCTGCCGT
GGCGCTGTGGAGCGGGCGGATGCCACCGCCGACGGTAGTGCTCGCCTGGGCGGCGGGGATCGCGGTAGCCATCGACCCAT
GGGCGGTGATGTCACCGGGCTTCTGGCTGTCATTTGGCGCGGTGGCGGTGATCTTCCTGGGCGCGCGGGGCGACGGCAGT
GGGGATGGAGGGGCGGTGGAGGAGCGGCAGGCGGATCCGAAAAGCTGTGTGAGCCGCTGTGTGAGCCGCTGGGTGAGTCG
GATTGGCGGCGTGGCTGCCGAGGCGGCGCGCACGCAATGGTCGGTGACTATCGGGCTCGTACCGTTGACGCTTCTGCTGT
TCGGGCAGGTCTCGGTGGTATCCGTGTTCGCCAATGCCGTGGCGATCCCGGTGGTTAGTCTGCTTGTTACGCCGCTGGCG
CTTGCTGGCGCGGTGTTGCCGCCTGGCTGGGCTGCGCCGCTGCTGTGGATCGCCCACAAAGCGCTGGAGTGGTTGGTTGG
GGGACTCGCGTGGCTGGCCGCGCCCGCGTGGGCAGTATGGGAGGCCGCGCACCCGGGTCCGGTGGCGACCGGGCTGGCAT
TGGCTGGTGTCTACGTCCTGCTCATCCCCCGTCCGTCGGATGCGAAAGGTGCCAGGCGAGTGCAGATCGTGCCGCGCTGG
TTGGGCGTGCTGCTGATGGTGCCGATGCTCTCGGCCGGGCCCGAGCCGGTGGAGGAAGGGGAAATGCGTGTGACAGCGCT
CGACGTCGGGCAGGGTGCAGCCGTGCTTGTGGAAACGCGCCGTCACGTGCTGCTCTACGACACTGGGCCTTCGTATGTGT
CGGGTGCCAGCGCAGGTGGTCAGGTGATCGTGCCTTATCTCCGCGCGACCGGGGTGCGGCATCTGGACATGCTGATGGTC
AGCCATGAGCATGACGACCACGCGGGCGGCGTTGAAGCCGTGCTGCAGGCCGTGCCGGTAGCGCGGGGGCTGACGGCGGA
AGGACCTGGGAACAAGCCACTGCCAGGCTTGCTGCAGGGGCGCGCGTGGCAGCCGTGTCTGGATGGCGTTGCGTGGCGTT
GGGATGGCGTGGACTTTGAGGTCCTGCACCCGACGGAAGAGGGTCTGGCGCGCCAGCGCTTGTCGGCCAACGCCCGGAGT
TGTGTGCTCCGCGTGGCAACGGCGCAGCGCAGCCTGCTGCTGACCGGCGACATTGGTGTATCGGAGGAGCGGCGGCTGAT
CGATAGCGAACTAGGTGAGCGATTGCGTGCGGATTTCCTGCTGGTGCCGCATCACGGCAGTGGCACGTCTTCACATGCGG
CATTCCTGCGGGCTGTACAACCCGAAGTGGCGGTGTTTCAGCTTGGCTTCGCGAACCGGCACAGGCATCCGCGTGAAGAT
GTCTGGCGGCGGTACGCGCGTGCGGGCGCGGCGCGGTATCGCACCGATGAAACCGGCGCGGTGTCGATCGTCACGGGCGG
CGGCGACTACGTGGTGACGTCGTTCCGTCAGCAACAGCGCCGTTATTGGCGAGACGCGCCGCCCGCGCCACGGTGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-201)

Competence protein (Competence)

(243-543)

Metallo-beta-lactamase superfamily (Lactamase_B)

(588-785)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1LPJ7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

46.689

100

0.481

Multiple sequence alignment