Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CWI26_RS09365 Genome accession   NZ_CP025043
Coordinates   1890198..1890887 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain AH681     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1885198..1895887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS09340 (CWI26_09340) - 1885738..1886292 (-) 555 WP_233486246.1 hypothetical protein -
  CWI26_RS12255 - 1886297..1886689 (-) 393 WP_233486247.1 hypothetical protein -
  CWI26_RS09350 (CWI26_09350) - 1887115..1888197 (-) 1083 WP_099876596.1 hypothetical protein -
  CWI26_RS09355 (CWI26_09355) - 1888382..1888753 (-) 372 WP_099876592.1 hypothetical protein -
  CWI26_RS09360 (CWI26_09360) - 1888984..1890108 (-) 1125 WP_099876589.1 AI-2E family transporter -
  CWI26_RS09365 (CWI26_09365) covR 1890198..1890887 (-) 690 WP_002942700.1 response regulator transcription factor Regulator
  CWI26_RS09370 (CWI26_09370) gndA 1890969..1892396 (-) 1428 WP_100881646.1 NADP-dependent phosphogluconate dehydrogenase -
  CWI26_RS09375 (CWI26_09375) - 1892493..1893032 (-) 540 WP_002942690.1 YceD family protein -
  CWI26_RS09380 (CWI26_09380) trxB 1893042..1893959 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  CWI26_RS09385 (CWI26_09385) - 1893973..1894197 (-) 225 WP_002936682.1 DUF4059 family protein -
  CWI26_RS09390 (CWI26_09390) - 1894215..1895558 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=257624 CWI26_RS09365 WP_002942700.1 1890198..1890887(-) (covR) [Streptococcus suis strain AH681]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=257624 CWI26_RS09365 WP_002942700.1 1890198..1890887(-) (covR) [Streptococcus suis strain AH681]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGATAATAATTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment