Detailed information NTG0257492

Bioinformatically predicted

Overview

• Name: comK/comK1
• Type: Regulator
• Locus tag: CWR44_RS07715
• Genome accession: NZ_CP025031
• Coordinates: 1572306..1572890 (-)
• Length: 194 a.a.
• NCBI ID: WP_011276196.1
• Uniprot ID: A0A2A1KAP4
• Organism: Staphylococcus haemolyticus strain SGAir0252
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1570395..1571711	1572306..1572890	flank	595

Gene organization within MGE regions

Location: 1570395..1572890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWR44_RS07700 (CWR44_07655)	-	1570395..1571711 (-)	1317	WP_011275929.1	ISL3 family transposase	-
CWR44_RS07715 (CWR44_07670)	comK/comK1	1572306..1572890 (-)	585	WP_011276196.1	competence protein ComK	Regulator

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 23002.43 Da
• Isoelectric Point: 9.2942

>NTDB_id=257492 CWR44_RS07715 WP_011276196.1 1572306..1572890(-) (comK/comK1) [Staphylococcus haemolyticus strain SGAir0252]
MTNISQSQNTVYIIRKGDMIIKPVIDDYEQTKGSEIWKYDSTIVSSPFKTQKIVERSCKFYGNSYISKKSETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENMWINMHYVHEIKPLKNRKCKIIFANHQTLTLNVSYHSIWHQYSNCIFYYYMVDKQ
SRMKSNNPEMPIDYEKTTLNIFEALSHYSLLQDK

Nucleotide

• Length: 585 bp

>NTDB_id=257492 CWR44_RS07715 WP_011276196.1 1572306..1572890(-) (comK/comK1) [Staphylococcus haemolyticus strain SGAir0252]
ATGACAAATATTTCTCAAAGCCAAAATACTGTATATATTATTCGAAAAGGAGATATGATAATCAAACCCGTCATTGATGA
TTATGAGCAAACAAAAGGATCAGAAATATGGAAATATGATTCCACAATAGTTTCAAGCCCATTCAAAACTCAAAAAATCG
TCGAACGCTCATGTAAATTTTATGGTAATAGCTATATTAGTAAGAAATCCGAAACACAACGAATTGCCGGCATTACTAGT
AAACCACCTATTTTATTGACTCCTCTCTTCCCCACTTATTTTTTCCCTACGCATTCAGACCGTTTAGAAGAAAACATGTG
GATTAATATGCATTATGTACATGAAATTAAACCTCTTAAAAATCGAAAATGTAAAATTATTTTTGCAAATCATCAAACAT
TAACACTTAATGTTTCCTACCACAGTATTTGGCACCAATACTCTAACTGCATTTTTTATTATTACATGGTCGATAAACAA
TCTCGTATGAAGTCAAACAATCCAGAAATGCCAATAGATTATGAGAAAACGACTTTAAATATTTTCGAAGCACTTTCACA
TTATTCACTATTACAAGATAAATAG

Domains

Predicted by InterproScan.

• ComK protein (ComK) (11-161)

3D structure

• AlphaFold DB: A0A2A1KAP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comK/comK1	Staphylococcus aureus MW2	68.617	96.907	0.665
comK/comK1	Staphylococcus aureus N315	68.617	96.907	0.665