Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CU118_RS00105 Genome accession   NZ_CP024998
Coordinates   23725..24294 (+) Length   189 a.a.
NCBI ID   WP_054190481.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 55-99-44     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 18725..29294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU118_RS00080 (CU118_00080) cysE 19938..20585 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CU118_RS00085 (CU118_00085) cysS 20569..21969 (+) 1401 WP_054190482.1 cysteine--tRNA ligase -
  CU118_RS00090 (CU118_00090) - 21962..22366 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CU118_RS00095 (CU118_00095) rlmB 22374..23120 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CU118_RS00100 (CU118_00100) - 23120..23644 (+) 525 WP_000664738.1 NYN domain-containing protein -
  CU118_RS00105 (CU118_00105) sigH 23725..24294 (+) 570 WP_054190481.1 sigma-70 family RNA polymerase sigma factor Regulator
  CU118_RS00110 (CU118_00110) rpmG 24409..24552 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CU118_RS00115 (CU118_00115) secE 24608..24790 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CU118_RS00120 (CU118_00120) nusG 24803..25351 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CU118_RS00125 (CU118_00125) rplK 25532..25954 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  CU118_RS00130 (CU118_00130) rplA 26162..26854 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CU118_RS00140 (CU118_00140) rplJ 27126..27626 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  CU118_RS00145 (CU118_00145) rplL 27668..28036 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CU118_RS00150 (CU118_00150) - 28211..28819 (+) 609 WP_054190480.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23085.90 Da        Isoelectric Point: 9.6015

>NTDB_id=256999 CU118_RS00105 WP_054190481.1 23725..24294(+) (sigH) [Staphylococcus aureus strain 55-99-44]
MEYDLTTQDSTTKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCKQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=256999 CU118_RS00105 WP_054190481.1 23725..24294(+) (sigH) [Staphylococcus aureus strain 55-99-44]
TTGGAATATGATTTGACAACTCAAGACAGTACAACCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTAAACAATATAAGCCAAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCTATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

97.884

100

0.979
  sigH Staphylococcus aureus N315

96.825

100

0.968

Multiple sequence alignment