Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CVO91_RS10140 Genome accession   NZ_CP024974
Coordinates   1984178..1984867 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain CZ130302     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1979178..1989867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS10115 (CVO91_10115) - 1979648..1980361 (-) 714 WP_002942704.1 nitroreductase family protein -
  CVO91_RS10120 (CVO91_10120) dnaI 1980358..1981257 (-) 900 WP_002942703.1 primosomal protein DnaI -
  CVO91_RS10125 (CVO91_10125) - 1981257..1982408 (-) 1152 WP_002942702.1 hypothetical protein -
  CVO91_RS10130 (CVO91_10130) nrdR 1982395..1982886 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  CVO91_RS10135 (CVO91_10135) - 1982958..1984088 (-) 1131 WP_002942701.1 AI-2E family transporter -
  CVO91_RS10140 (CVO91_10140) covR 1984178..1984867 (-) 690 WP_002942700.1 winged helix-turn-helix domain-containing protein Regulator
  CVO91_RS10145 (CVO91_10145) gndA 1984949..1986376 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  CVO91_RS10150 (CVO91_10150) - 1986473..1987012 (-) 540 WP_002942690.1 DUF177 domain-containing protein -
  CVO91_RS10155 (CVO91_10155) trxB 1987022..1987939 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  CVO91_RS10160 (CVO91_10160) - 1987953..1988177 (-) 225 WP_002936682.1 DUF4059 family protein -
  CVO91_RS10165 (CVO91_10165) - 1988195..1989538 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=256941 CVO91_RS10140 WP_002942700.1 1984178..1984867(-) (covR) [Streptococcus suis strain CZ130302]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=256941 CVO91_RS10140 WP_002942700.1 1984178..1984867(-) (covR) [Streptococcus suis strain CZ130302]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGATAATAATTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment