Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV724_RS07420 Genome accession   NZ_CP024952
Coordinates   1527250..1527987 (-) Length   245 a.a.
NCBI ID   WP_000660517.1    Uniprot ID   I9RM86
Organism   Helicobacter pylori strain B125A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1522250..1532987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV724_RS07400 (CV724_07425) gmd 1522472..1523617 (-) 1146 WP_145727429.1 GDP-mannose 4,6-dehydratase -
  CV724_RS07405 (CV724_07430) - 1523646..1525058 (-) 1413 WP_145727430.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV724_RS07410 (CV724_07435) comB10 1525129..1526259 (-) 1131 WP_145727431.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV724_RS07415 (CV724_07440) comB9 1526252..1527250 (-) 999 WP_145727432.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV724_RS07420 (CV724_07445) comB8 1527250..1527987 (-) 738 WP_000660517.1 virB8 family protein Machinery gene
  CV724_RS07425 (CV724_07450) comB7 1527984..1528097 (-) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV724_RS07430 (CV724_07455) comB6 1528113..1529168 (-) 1056 WP_145727433.1 P-type conjugative transfer protein TrbL Machinery gene
  CV724_RS07435 (CV724_07460) - 1529176..1530180 (-) 1005 WP_145727518.1 PDZ domain-containing protein -
  CV724_RS08350 - 1530180..1530473 (-) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  CV724_RS08355 panD 1530483..1530833 (-) 351 WP_108310021.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28544.77 Da        Isoelectric Point: 8.9546

>NTDB_id=256667 CV724_RS07420 WP_000660517.1 1527250..1527987(-) (comB8) [Helicobacter pylori strain B125A]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=256667 CV724_RS07420 WP_000660517.1 1527250..1527987(-) (comB8) [Helicobacter pylori strain B125A]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCATCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAACGAAAACAAGTTGGTGTATGAAAAGCGTTATAAAATTGTGCTGAGTTATTTGTTTG
ACACCCCAGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I9RM86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.98

Multiple sequence alignment