Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV726_RS00945 Genome accession   NZ_CP024950
Coordinates   199856..200599 (+) Length   247 a.a.
NCBI ID   WP_145939925.1    Uniprot ID   -
Organism   Helicobacter pylori strain B130A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194856..205599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV726_RS00920 (CV726_00925) panD 197023..197376 (+) 354 WP_000142239.1 aspartate 1-decarboxylase -
  CV726_RS00925 (CV726_00930) - 197379..197672 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  CV726_RS00930 (CV726_00935) - 197672..198667 (+) 996 WP_145940748.1 PDZ domain-containing protein -
  CV726_RS00935 (CV726_00940) comB6 198675..199730 (+) 1056 WP_145939924.1 P-type conjugative transfer protein TrbL Machinery gene
  CV726_RS00940 (CV726_00945) comB7 199746..199859 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV726_RS00945 (CV726_00950) comB8 199856..200599 (+) 744 WP_145939925.1 virB8 family protein Machinery gene
  CV726_RS00950 (CV726_00955) comB9 200599..201588 (+) 990 WP_145939926.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV726_RS00955 (CV726_00960) comB10 201581..202711 (+) 1131 WP_001045759.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV726_RS00960 (CV726_00965) - 202781..204193 (+) 1413 WP_145939927.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV726_RS00965 (CV726_00970) gmd 204223..205368 (+) 1146 WP_145939928.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28750.01 Da        Isoelectric Point: 9.2667

>NTDB_id=256619 CV726_RS00945 WP_145939925.1 199856..200599(+) (comB8) [Helicobacter pylori strain B130A]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFENLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=256619 CV726_RS00945 WP_145939925.1 199856..200599(+) (comB8) [Helicobacter pylori strain B130A]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAACGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAAATTTGATTAAAACCCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTTTTGAACGAAAACAAGCTAGTGTATGAAAAGCGTTATAAAATCGTGCTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
GCGCCGACTAACAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

98.785

100

0.988

Multiple sequence alignment