Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV727_RS07495 Genome accession   NZ_CP024949
Coordinates   1520811..1521554 (-) Length   247 a.a.
NCBI ID   WP_000660569.1    Uniprot ID   J0FAL2
Organism   Helicobacter pylori strain B136A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1515811..1526554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV727_RS07475 (CV727_07470) gmd 1516045..1517190 (-) 1146 WP_145821305.1 GDP-mannose 4,6-dehydratase -
  CV727_RS07480 (CV727_07475) - 1517219..1518631 (-) 1413 WP_145821307.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV727_RS07485 (CV727_07480) comB10 1518702..1519838 (-) 1137 WP_145821308.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV727_RS07490 (CV727_07485) comB9 1519831..1520811 (-) 981 WP_145821310.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV727_RS07495 (CV727_07490) comB8 1520811..1521554 (-) 744 WP_000660569.1 virB8 family protein Machinery gene
  CV727_RS07500 (CV727_07495) comB7 1521551..1521664 (-) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV727_RS07505 (CV727_07500) comB6 1521680..1522735 (-) 1056 WP_145821557.1 P-type conjugative transfer protein TrbL Machinery gene
  CV727_RS07510 (CV727_07505) - 1522743..1523747 (-) 1005 WP_145821312.1 PDZ domain-containing protein -
  CV727_RS07515 (CV727_07510) - 1523747..1524049 (-) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  CV727_RS07520 (CV727_07515) panD 1524052..1524405 (-) 354 WP_108338030.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28736.93 Da        Isoelectric Point: 8.9546

>NTDB_id=256604 CV727_RS07495 WP_000660569.1 1520811..1521554(-) (comB8) [Helicobacter pylori strain B136A]
MKEKPFNSEQLNYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDAPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=256604 CV727_RS07495 WP_000660569.1 1520811..1521554(-) (comB8) [Helicobacter pylori strain B136A]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGAACTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGCATTCTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATCTAT
GCACAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACGCCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGTTACAGCATCACTGAAATC
GCGCCGACTAATAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J0FAL2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment