Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   CVD07_RS14945 Genome accession   NZ_CP024897
Coordinates   3025421..3026065 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain CN026     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3020421..3031065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVD07_RS14910 (CVD07_14965) - 3021606..3022037 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  CVD07_RS14915 (CVD07_14970) - 3022037..3022378 (+) 342 WP_022553706.1 Na(+)/H(+) antiporter subunit C -
  CVD07_RS14920 (CVD07_14975) - 3022371..3023852 (+) 1482 WP_100261979.1 Na+/H+ antiporter subunit D -
  CVD07_RS14925 (CVD07_14980) - 3023858..3024334 (+) 477 WP_014418760.1 Na+/H+ antiporter subunit E -
  CVD07_RS14930 (CVD07_14985) - 3024334..3024618 (+) 285 WP_017419420.1 Na(+)/H(+) antiporter subunit F1 -
  CVD07_RS14935 (CVD07_14990) mnhG 3024602..3024976 (+) 375 WP_095273327.1 monovalent cation/H(+) antiporter subunit G -
  CVD07_RS14940 (CVD07_14995) - 3025016..3025399 (-) 384 WP_014418761.1 hotdog fold thioesterase -
  CVD07_RS14945 (CVD07_15000) comA 3025421..3026065 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  CVD07_RS14950 (CVD07_15005) comP 3026146..3028437 (-) 2292 WP_100261980.1 histidine kinase Regulator
  CVD07_RS14955 (CVD07_15010) comX 3028449..3028613 (-) 165 WP_007613432.1 competence pheromone ComX -
  CVD07_RS14960 (CVD07_15015) - 3028613..3029491 (-) 879 WP_032860494.1 polyprenyl synthetase family protein -
  CVD07_RS14965 (CVD07_15020) degQ 3029676..3029816 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  CVD07_RS14975 (CVD07_15030) - 3030282..3030623 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=256270 CVD07_RS14945 WP_014418762.1 3025421..3026065(-) (comA) [Bacillus velezensis strain CN026]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=256270 CVD07_RS14945 WP_014418762.1 3025421..3026065(-) (comA) [Bacillus velezensis strain CN026]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment