Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DMB38_RS28775 Genome accession   NZ_CP029618
Coordinates   6591197..6591859 (+) Length   220 a.a.
NCBI ID   WP_125937587.1    Uniprot ID   -
Organism   Streptomyces sp. WAC 06738     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6586197..6596859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB38_RS28765 (DMB38_28755) - 6588181..6589674 (+) 1494 WP_125937585.1 glycosyltransferase family 39 protein -
  DMB38_RS28770 (DMB38_28760) - 6589749..6591200 (+) 1452 WP_240662515.1 histidine kinase -
  DMB38_RS28775 (DMB38_28765) vraR 6591197..6591859 (+) 663 WP_125937587.1 response regulator transcription factor Regulator
  DMB38_RS28780 (DMB38_28770) - 6591865..6593022 (-) 1158 WP_125937588.1 GTP-binding protein -
  DMB38_RS28785 (DMB38_28775) - 6593026..6593277 (-) 252 WP_125937589.1 type B 50S ribosomal protein L31 -
  DMB38_RS28790 (DMB38_28780) rpmG 6593307..6593471 (-) 165 WP_125937590.1 50S ribosomal protein L33 -
  DMB38_RS28795 (DMB38_28785) - 6593649..6593852 (+) 204 WP_164716134.1 hypothetical protein -
  DMB38_RS28800 (DMB38_28790) - 6593943..6594233 (+) 291 WP_125937592.1 hypothetical protein -
  DMB38_RS28805 (DMB38_28795) - 6594247..6594693 (-) 447 WP_125937593.1 VOC family protein -
  DMB38_RS28810 (DMB38_28800) - 6594722..6595777 (-) 1056 WP_125937594.1 Gfo/Idh/MocA family oxidoreductase -
  DMB38_RS28815 (DMB38_28805) - 6595774..6596721 (-) 948 WP_125937595.1 amidohydrolase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23396.07 Da        Isoelectric Point: 4.9612

>NTDB_id=255160 DMB38_RS28775 WP_125937587.1 6591197..6591859(+) (vraR) [Streptomyces sp. WAC 06738]
MTIRVLITDDQSMVREGFTVLLDAQPGIEVVGEAADGGEAVEQVGLLAPDVVLMDIRMPEVNGLEATRRIAGAGLGTKVL
ILTTYHLDEYVYEALRAGASGFLLKDASARQLAEGVRTVAAGEALLAPTVTKRLITVFAERKPVLNLPAETRVAGLTGRE
TEVLALIAQGLSNAEIAARLVVAESTVKTHVGRILEKLGLRDRTQAAIFAYETRLVQPAG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=255160 DMB38_RS28775 WP_125937587.1 6591197..6591859(+) (vraR) [Streptomyces sp. WAC 06738]
GTGACCATCCGGGTGCTCATCACCGACGACCAGTCCATGGTGCGCGAGGGGTTCACCGTGCTGCTCGACGCCCAGCCCGG
GATCGAGGTCGTCGGCGAGGCCGCCGACGGCGGCGAGGCGGTGGAGCAGGTGGGCCTGCTCGCACCCGACGTCGTGCTCA
TGGACATCCGGATGCCGGAGGTCAACGGGCTGGAGGCGACCCGCCGGATCGCCGGCGCCGGGCTCGGCACCAAGGTCCTC
ATCCTCACCACGTACCACCTCGACGAGTACGTCTACGAGGCGCTGCGCGCCGGCGCCAGCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAGCTCGCCGAGGGCGTCCGCACCGTCGCCGCCGGCGAGGCCCTGCTCGCGCCCACCGTCACCAAGCGCC
TGATCACCGTCTTCGCCGAGCGCAAGCCGGTGCTGAACCTCCCGGCGGAGACCCGCGTCGCCGGTCTCACCGGCCGCGAG
ACGGAGGTCCTGGCCCTCATCGCGCAGGGGCTGTCCAACGCCGAGATCGCGGCCCGCCTCGTGGTCGCCGAGTCCACGGT
CAAGACCCATGTGGGACGGATCCTGGAGAAGCTGGGGCTGCGGGACCGCACCCAGGCCGCGATCTTCGCCTACGAGACCC
GCCTCGTACAGCCCGCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.857

98.636

0.423
  degU Bacillus subtilis subsp. subtilis str. 168

41.071

100

0.418