Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DMB38_RS19135 Genome accession   NZ_CP029618
Coordinates   4404201..4404875 (+) Length   224 a.a.
NCBI ID   WP_125936210.1    Uniprot ID   -
Organism   Streptomyces sp. WAC 06738     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4399201..4409875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB38_RS19115 (DMB38_19110) - 4399620..4400351 (-) 732 WP_047017116.1 ABC transporter permease -
  DMB38_RS19120 (DMB38_19115) - 4400436..4401599 (+) 1164 WP_125936207.1 betaine/proline/choline family ABC transporter ATP-binding protein -
  DMB38_RS19125 (DMB38_19120) - 4401704..4402822 (-) 1119 WP_125936208.1 SAM-dependent methyltransferase -
  DMB38_RS19130 (DMB38_19125) - 4402917..4404143 (+) 1227 WP_125936209.1 sensor histidine kinase -
  DMB38_RS19135 (DMB38_19130) vraR 4404201..4404875 (+) 675 WP_125936210.1 response regulator transcription factor Regulator
  DMB38_RS19140 (DMB38_19135) - 4404998..4406086 (-) 1089 WP_125936211.1 DUF5937 family protein -
  DMB38_RS19145 (DMB38_19140) - 4406083..4407261 (-) 1179 WP_125936212.1 beta-eliminating lyase-related protein -
  DMB38_RS19150 (DMB38_19145) - 4407500..4408408 (+) 909 WP_125936213.1 DUF2520 domain-containing protein -
  DMB38_RS19155 (DMB38_19150) panC 4408421..4409380 (+) 960 WP_125936214.1 pantoate--beta-alanine ligase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24144.05 Da        Isoelectric Point: 5.1324

>NTDB_id=255134 DMB38_RS19135 WP_125936210.1 4404201..4404875(+) (vraR) [Streptomyces sp. WAC 06738]
MTIRVMLVDDQALLRTGFRMVLAAQPDMDVVAEAGDGDEAVQLLAVTKVDVVLMDVRMPRLDGVEATRRICADKPAEAPP
KVLILTTFDLDEYAFSALQAGASGFMLKDVPPGDLLSAIRAVHSGDAVVAPSTTRRLIDRFTAVMPAPAGERAHPELRRL
TDREREVLLLIAQGLSNGEIAAQLVLSEATVKTHVGRILTKLELRDRVQAVVLAYETGLVRAGG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=255134 DMB38_RS19135 WP_125936210.1 4404201..4404875(+) (vraR) [Streptomyces sp. WAC 06738]
GTGACGATCCGGGTCATGCTCGTGGACGACCAGGCGCTGCTGCGCACCGGCTTCCGGATGGTGCTGGCCGCCCAGCCCGA
CATGGACGTCGTCGCGGAGGCCGGGGACGGCGACGAGGCGGTGCAGCTCCTCGCCGTCACGAAGGTGGACGTCGTGCTCA
TGGACGTACGCATGCCGCGCCTCGACGGTGTCGAGGCGACGCGGCGCATCTGCGCGGACAAGCCGGCGGAGGCGCCGCCG
AAGGTGCTGATCCTGACCACCTTCGACCTGGACGAGTACGCCTTCTCCGCGCTGCAGGCCGGGGCGTCGGGCTTCATGCT
CAAGGACGTGCCGCCCGGTGACCTGCTGAGCGCGATCCGGGCCGTGCACAGCGGCGACGCGGTCGTCGCGCCGAGCACGA
CGCGGCGGCTCATCGACCGGTTCACGGCCGTGATGCCCGCCCCGGCGGGGGAGCGGGCGCACCCGGAGCTGAGGCGGCTG
ACGGACCGGGAGCGCGAGGTGCTGCTCCTGATCGCACAGGGGCTGTCGAACGGGGAGATCGCGGCGCAACTGGTGCTGTC
GGAGGCGACGGTGAAGACACATGTGGGGCGGATCCTCACGAAGCTGGAGCTGCGGGACAGGGTGCAGGCGGTGGTCCTGG
CCTACGAGACGGGTCTGGTACGGGCCGGAGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-214)

Response regulator receiver domain (Response_reg)

(5-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.09

99.107

0.397
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.393