Detailed information NTG0254811

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CSW12_RS05380
• Genome accession: NZ_CP024655
• Coordinates: 1024762..1027362 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365401.1
• Uniprot ID: A0A9W5QJY6
• Organism: Bacillus cereus strain MLY1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1019762..1032362

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSW12_RS05330 (CSW12_05350)	-	1019846..1020088 (+)	243	WP_000450402.1	hypothetical protein	-
CSW12_RS05335 (CSW12_05355)	-	1020221..1020484 (+)	264	WP_141548262.1	hypothetical protein	-
CSW12_RS05340 (CSW12_05360)	prsA	1020524..1021381 (-)	858	WP_001214215.1	peptidylprolyl isomerase PrsA	-
CSW12_RS05345 (CSW12_05365)	-	1021511..1021642 (-)	132	WP_001120851.1	DUF3941 domain-containing protein	-
CSW12_RS05350 (CSW12_05370)	-	1021743..1022600 (+)	858	WP_000364432.1	YitT family protein	-
CSW12_RS05355 (CSW12_05375)	-	1022626..1022823 (-)	198	WP_000527407.1	DUF3813 domain-containing protein	-
CSW12_RS05360 (CSW12_05380)	-	1022824..1022964 (-)	141	WP_000516816.1	hypothetical protein	-
CSW12_RS05365 (CSW12_05385)	-	1023070..1023879 (-)	810	WP_001041231.1	Cof-type HAD-IIB family hydrolase	-
CSW12_RS05375 (CSW12_05395)	-	1024371..1024550 (+)	180	WP_016082481.1	YjzC family protein	-
CSW12_RS05380 (CSW12_05400)	clpC	1024762..1027362 (+)	2601	WP_000365401.1	ATP-dependent chaperone ClpB	Regulator
CSW12_RS05385 (CSW12_05405)	-	1027401..1027583 (-)	183	WP_001211116.1	YjzD family protein	-
CSW12_RS05390 (CSW12_05410)	-	1027740..1028474 (+)	735	WP_000028691.1	hydrolase	-
CSW12_RS05395 (CSW12_05415)	-	1028504..1029376 (+)	873	WP_001986101.1	NAD-dependent epimerase/dehydratase family protein	-
CSW12_RS05400 (CSW12_05420)	comZ	1029431..1029607 (+)	177	WP_001986215.1	ComZ family protein	Regulator
CSW12_RS05405 (CSW12_05425)	fabH	1029998..1030930 (+)	933	WP_001100533.1	beta-ketoacyl-ACP synthase III	-
CSW12_RS05410 (CSW12_05430)	fabF	1030962..1032200 (+)	1239	WP_000412656.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97382.35 Da
• Isoelectric Point: 5.1561

>NTDB_id=254811 CSW12_RS05380 WP_000365401.1 1024762..1027362(+) (clpC) [Bacillus cereus strain MLY1]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQGAESLIKKKPSVTGSGAE
VGKLYVTSALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRDLVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=254811 CSW12_RS05380 WP_000365401.1 1024762..1027362(+) (clpC) [Bacillus cereus strain MLY1]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAAGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTAAAGCAAGGTGCTGAAAGTTTAATTAAAAAGAAACCTTCTGTAACGGGGAGCGGTGCAGAA
GTTGGAAAATTGTATGTAACGAGCGCTCTGCAACAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTGTTGCTTGCTTTTTCTGAAGAAAAAGGCGATATAAATCAATTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACGAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATCGATCCTGTAATCGGCCGTGA
TAGTGAAATACGACGTGTAATCCGTATTCTTTCACGTAAAACGAAAAACAATCCGGTTTTAATTGGGGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGCTAGCCCAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTGAAAGATAGAACGATT
TTTGCGTTAGATATGAGTGCACTCGTAGCTGGTGCGAAATTCCGTGGTGAGTTCGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGACGCATTTTATTATTCATTGATGAACTTCATACAATAGTTGGAGCTGGTAAAACAGAAG
GAGCCATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACGACGCTCGAT
GAATATCGCAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCAATTTTACGTGGATTAAAAGAACGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGTGCGATTG
TAGCAGCGTCAGTTTTATCAGATCGATATATTTCAGATCGATTCTTACCTGATAAAGCAATTGACCTTGTTGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTGGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAAACGGATCGTGGTAGCCAAGAGCGTCTAAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCAAAGTGGGAGAAAGAAAAAGAAGACATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAACGTCTGCGTCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCCGAACTTCGTCACGG
GAAAATTCCAGCAATTGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAAATTGCAGATATTGTTTCACGCTGGACGGGTATTCCTGTTGCAAAACTCGTGGAAGGT
GAACGCGAGAAATTATTACGCTTAGAGCAAATCTTATCAGAGCGTGTCATCGGACAAGAGGAAGCAGTAAGCTTAGTGTC
AGACGCAGTTCTTCGTGCTCGCGCTGGTATTAAAGATCCGAACCGCCCGATTGGTTCTTTCATCTTCTTAGGACCAACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATTGACATG
TCTGAGTATATGGAGAAACACGCAGTGTCACGCTTAATTGGTGCACCTCCTGGATATGTAGGATATGAGGAAGGTGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCATATTCCGTTGTTTTATTAGATGAAATTGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGGCGCATTACAGATTCGCAAGGTCGTACAGTGGACTTTAAAAATACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTACTAGATGGATTAGAAGAAGATGGTTCGATTAAAGAGGAATCAAGAGA
TCTTGTAATGGGACAATTAAGAGGACATTTCCGCCCTGAATTTTTAAACCGTGTTGATGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGCATTGTTGATAAAATTGTAAAAGAACTACAAGGTCGTCTAGCTGACCGTCACATTACA
GTAGAATTAACAGATGCAGCAAAAGAATTTGTTGTAGAAGCTGGTTTCGACCCAATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCACGAGAATTAATTGCAGGAACAATTACTGACAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• AAA lid domain (AAA_lid_9) (345-447)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48	100	0.485
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.153	100	0.425
clpC	Lactococcus lactis subsp. cremoris KW2	47.059	82.448	0.388