Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DLJ52_RS08850 Genome accession   NZ_CP029559
Coordinates   1820283..1820933 (-) Length   216 a.a.
NCBI ID   WP_019770084.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1815283..1825933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS08830 (DLJ52_08830) - 1816546..1817184 (+) 639 WP_094966549.1 YigZ family protein -
  DLJ52_RS08835 (DLJ52_08835) cysK 1817284..1818213 (+) 930 WP_019769631.1 cysteine synthase A -
  DLJ52_RS08840 (DLJ52_08840) - 1818432..1818782 (-) 351 WP_109982744.1 S1 RNA-binding domain-containing protein -
  DLJ52_RS08845 (DLJ52_08845) - 1818782..1820179 (-) 1398 WP_109982745.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DLJ52_RS08850 (DLJ52_08850) vraR 1820283..1820933 (-) 651 WP_019770084.1 response regulator transcription factor Regulator
  DLJ52_RS08855 (DLJ52_08855) - 1820911..1821954 (-) 1044 WP_021673931.1 sensor histidine kinase -
  DLJ52_RS08860 (DLJ52_08860) liaF 1821951..1822649 (-) 699 WP_019770059.1 cell wall-active antibiotics response protein LiaF -
  DLJ52_RS08865 (DLJ52_08865) pknB 1823127..1825001 (-) 1875 WP_109982746.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DLJ52_RS08870 (DLJ52_08870) - 1824998..1825741 (-) 744 WP_002960300.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24260.91 Da        Isoelectric Point: 4.6313

>NTDB_id=254128 DLJ52_RS08850 WP_019770084.1 1820283..1820933(-) (vraR) [Streptococcus sobrinus strain NIDR 6715-15]
MKTMDKTKIILVDDHEMVRLGLKSFFNMQPDIEVIGEADNGKDGVEMALELRPDVVVMDLVMPEMDGVEATLAILKEWKA
AKILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVAQGQVAIETEVDQKIKYHDQHPDLHDDLTARERDVLA
LLAKGYDNQTIADELFISLKTVKTHVSNILAKLNVEDRTQAVVYAFQHNLVPQEDQ

Nucleotide


Download         Length: 651 bp        

>NTDB_id=254128 DLJ52_RS08850 WP_019770084.1 1820283..1820933(-) (vraR) [Streptococcus sobrinus strain NIDR 6715-15]
ATGAAAACGATGGACAAGACTAAAATTATACTGGTTGATGATCATGAAATGGTTCGTCTAGGATTAAAGAGCTTCTTTAA
TATGCAGCCGGACATTGAAGTTATCGGCGAAGCTGATAACGGTAAGGACGGGGTTGAAATGGCACTGGAGCTGAGACCAG
ACGTTGTCGTCATGGACCTGGTCATGCCTGAGATGGATGGAGTTGAAGCCACTCTAGCGATTCTTAAGGAATGGAAGGCT
GCCAAAATTCTGGTTCTGACCTCCTATTTGGATAATGAAAAAATCTACCCTGTCATTGAGGCTGGAGCCAAGGGCTATAT
GCTCAAGACCTCCAGTGCTGCTGAAATTCTCAACAGTATTCGCAAGGTCGCCCAGGGCCAAGTGGCCATTGAAACCGAGG
TTGATCAAAAGATTAAATACCACGATCAGCACCCCGACCTCCACGATGATTTGACAGCCCGAGAACGGGACGTTCTAGCC
CTCTTGGCCAAGGGTTACGACAATCAAACCATCGCCGATGAACTCTTTATTTCGCTCAAGACGGTTAAAACCCATGTTTC
AAACATTTTAGCTAAACTCAATGTTGAAGATCGAACCCAGGCTGTCGTCTATGCCTTCCAGCACAATCTGGTCCCCCAGG
AAGACCAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(151-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.244

94.907

0.477
  degU Bacillus subtilis subsp. subtilis str. 168

36.726

100

0.384