Detailed information NTG0254011

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: DKG71_RS23935
• Genome accession: NZ_CP029541
• Coordinates: 5594834..5595958 (-)
• Length: 374 a.a.
• NCBI ID: WP_026170238.1
• Uniprot ID: A0A640THM3
• Organism: Streptomyces sp. NEAU-S7GS2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5589834..5600958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DKG71_RS23915 (DKG71_23915)	-	5590169..5591803 (+)	1635	WP_109891724.1	GAF domain-containing protein	-
DKG71_RS23920 (DKG71_23920)	-	5591912..5592613 (-)	702	WP_109891726.1	response regulator transcription factor	-
DKG71_RS23925 (DKG71_23925)	-	5592896..5594224 (+)	1329	WP_109891728.1	globin domain-containing protein	-
DKG71_RS23930 (DKG71_23930)	-	5594393..5594809 (+)	417	WP_202466676.1	pyridoxamine 5'-phosphate oxidase family protein	-
DKG71_RS23935 (DKG71_23935)	disA	5594834..5595958 (-)	1125	WP_026170238.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
DKG71_RS23940 (DKG71_23940)	radA	5596084..5597496 (-)	1413	WP_018093005.1	DNA repair protein RadA	Machinery gene
DKG71_RS23945 (DKG71_23945)	-	5597747..5599498 (+)	1752	WP_109891730.1	sigma-70 family RNA polymerase sigma factor	-
DKG71_RS23950 (DKG71_23950)	-	5599550..5600422 (-)	873	WP_109891732.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40289.13 Da
• Isoelectric Point: 4.9306

>NTDB_id=254011 DKG71_RS23935 WP_026170238.1 5594834..5595958(-) (disA) [Streptomyces sp. NEAU-S7GS2]
MAANDRASTPGRSGGSSSTESLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVETMCTGGFVLDVEFTATRLR
ELCKLDGALVLDKDITKILRAGVQLVPDASIPTEETGTRHRTAQRVSIQAGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALAELDALSHTELLELPIVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGT
VIDRLVDHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=254011 DKG71_RS23935 WP_026170238.1 5594834..5595958(-) (disA) [Streptomyces sp. NEAU-S7GS2]
GTGGCAGCCAACGACCGGGCATCGACTCCCGGCAGGTCCGGTGGCAGTTCCTCCACCGAGAGCCTGATGCGCGCCTCACT
GAGCGCCGTCGCGCCCGGTACGGCCCTGCGCGACGGACTGGAACGCATCCTCCGCGGCAACACCGGCGGACTGATCGTGC
TGGGCTTCGACAAGACCGTCGAGACCATGTGCACCGGCGGTTTCGTCCTCGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGTGCGCTGGTCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGAGTCCAGCTGGTCCC
GGACGCCTCCATCCCGACGGAGGAGACCGGCACCCGCCACCGCACCGCCCAGCGCGTCTCCATCCAGGCCGGCTTCCCGG
TCGTCTCCGTCAGCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCGAGCGCCGCGTCCTGGAGGAGTCGGCCGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCCGGCACCCTCTC
CGCCCTGGAGATCGAGGACTTGGTCACGGTCCGCGATGTCACCGCGGTCGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTCGTCGAGCTCGGCACGGACGGCCGGCTGCTCGCCCTCCAGCTGGAGGAGCTGATCGCC
GGCGTGGAGCCCGAGCGGGAGCTGGTCGTCCGCGACTACGTCCCCGAGCCGACCGCCAAGCGCTCCCGCACGGTCGCCGA
GGCGCTCGCCGAGCTGGACGCCCTCAGCCACACCGAGCTCCTCGAACTCCCCATCGTGGCCCGCGCGCTGGGCTACAGCG
GCGCCCCCGAGACCCTGGACTCCGCGGTCTCACCGCGCGGCTTCCGCCTGCTGGCGAAGGTCCCCCGGCTGCCCGGCACG
GTCATCGACCGCCTCGTCGACCACTTCGGCGGCCTGCAGAAGCTCCTCGCGGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCTCGGTCCGCGAGGGCCTGTCACGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-296)

3D structure

• AlphaFold DB: A0A640THM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.665	92.513	0.422