Detailed information NTG0025400

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: SAUSA300_RS08435
• Genome accession: NC_007793
• Coordinates: 1698230..1700431 (-)
• Length: 733 a.a.
• NCBI ID: WP_001548978.1
• Uniprot ID: A0AB73FPE0
• Organism: Staphylococcus aureus subsp. aureus USA300_FPR3757
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1693230..1705431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAUSA300_RS08420 (SAUSA300_1544)	lepA	1694734..1696557 (-)	1824	WP_000368341.1	translation elongation factor 4	-
SAUSA300_RS08425 (SAUSA300_1545)	rpsT	1696903..1697154 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
SAUSA300_RS08430 (SAUSA300_1546)	holA	1697199..1698173 (-)	975	WP_001282562.1	DNA polymerase III subunit delta	-
SAUSA300_RS08435 (SAUSA300_1547)	comEC	1698230..1700431 (-)	2202	WP_001548978.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SAUSA300_RS08440 (SAUSA300_1548)	-	1700436..1700897 (-)	462	WP_000439693.1	ComE operon protein 2	-
SAUSA300_RS08445 (SAUSA300_1549)	comEA	1700989..1701675 (-)	687	WP_001792568.1	ComEA family DNA-binding protein	Machinery gene
SAUSA300_RS08450 (SAUSA300_1550)	-	1701715..1702431 (-)	717	WP_000084829.1	class I SAM-dependent DNA methyltransferase	-
SAUSA300_RS08455 (SAUSA300_1551)	rsfS	1702434..1702787 (-)	354	WP_001088022.1	ribosome silencing factor	-
SAUSA300_RS08460 (SAUSA300_1552)	yqeK	1702788..1703372 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
SAUSA300_RS08465 (SAUSA300_1553)	nadD	1703362..1703931 (-)	570	WP_000725162.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
SAUSA300_RS08470 (SAUSA300_1554)	yhbY	1703934..1704224 (-)	291	WP_000955231.1	ribosome assembly RNA-binding protein YhbY	-
SAUSA300_RS08475 (SAUSA300_1555)	aroE	1704228..1705034 (-)	807	WP_000666761.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84881.97 Da
• Isoelectric Point: 10.0277

>NTDB_id=25400 SAUSA300_RS08435 WP_001548978.1 1698230..1700431(-) (comEC) [Staphylococcus aureus subsp. aureus USA300_FPR3757]
MLFVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSAWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEVNEQFKERVKEIVIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLVITKQIKIKSIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPSFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIVFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSSSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=25400 SAUSA300_RS08435 WP_001548978.1 1698230..1700431(-) (comEC) [Staphylococcus aureus subsp. aureus USA300_FPR3757]
TTGCTGTTTGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTACTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCGCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAGTTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGTTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTTTTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACTCTTGT
ACTGGTTATTACTAAGCAAATTAAAATAAAGAGTATTCAGCTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAGCTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAGT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGCGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAGTATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAATATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAGCTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (183-441)

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.363	100	0.984
comEC	Staphylococcus aureus MW2	97.954	100	0.98