Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DKG71_RS13730 Genome accession   NZ_CP029541
Coordinates   3297840..3298520 (+) Length   226 a.a.
NCBI ID   WP_093644332.1    Uniprot ID   A0A640TRR5
Organism   Streptomyces sp. NEAU-S7GS2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3292840..3303520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DKG71_RS13710 (DKG71_13710) - 3293075..3293728 (+) 654 WP_018088043.1 TetR/AcrR family transcriptional regulator -
  DKG71_RS13715 (DKG71_13715) - 3293985..3295199 (+) 1215 WP_109889475.1 alpha/beta hydrolase -
  DKG71_RS13720 (DKG71_13720) - 3295407..3296288 (+) 882 WP_109889477.1 DUF4429 domain-containing protein -
  DKG71_RS13725 (DKG71_13725) - 3296452..3297843 (+) 1392 WP_109889480.1 sensor histidine kinase -
  DKG71_RS13730 (DKG71_13730) vraR 3297840..3298520 (+) 681 WP_093644332.1 response regulator transcription factor Regulator
  DKG71_RS13735 (DKG71_13735) - 3298681..3299925 (+) 1245 WP_239471827.1 acyltransferase -
  DKG71_RS13740 (DKG71_13740) - 3300003..3301019 (-) 1017 WP_093644330.1 aldo/keto reductase -
  DKG71_RS13745 (DKG71_13745) - 3301027..3301515 (-) 489 WP_202465974.1 MerR family transcriptional regulator -
  DKG71_RS13750 (DKG71_13750) - 3301678..3302499 (+) 822 WP_109896120.1 serine hydrolase domain-containing protein -
  DKG71_RS13755 (DKG71_13755) - 3302546..3303217 (-) 672 WP_174876396.1 pirin family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24221.01 Da        Isoelectric Point: 5.7598

>NTDB_id=253989 DKG71_RS13730 WP_093644332.1 3297840..3298520(+) (vraR) [Streptomyces sp. NEAU-S7GS2]
MTTRVIIVDDQAMVRAGFAALLAAQSDIDVVGDAPDGVQGVALSRRTHPDVVLMDVRMPEMDGLAAARQLLDPPVGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARSGPVTRKGRPSLRLNG
LTPRETEVLELIARGLSNQEIADALIVAEQTVKTHVSRVLAKLDLRDRAQAVIFAYESGLVSPGER

Nucleotide


Download         Length: 681 bp        

>NTDB_id=253989 DKG71_RS13730 WP_093644332.1 3297840..3298520(+) (vraR) [Streptomyces sp. NEAU-S7GS2]
ATGACCACCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGTGCGGGCTTTGCCGCGCTGCTCGCCGCGCAGAGCGA
CATCGATGTGGTGGGCGATGCCCCGGATGGGGTGCAGGGCGTCGCCCTGAGCCGCCGGACGCACCCCGATGTGGTGCTGA
TGGATGTGCGGATGCCGGAGATGGACGGTCTGGCGGCGGCCCGTCAGCTGCTCGATCCGCCCGTCGGCGTCATCCATCGC
CCGAAGGTGCTGATGCTGACCACGTTCGACGTCGACGACTATGTCTACGAGGCGCTGCGCGCCGGGGCGTCCGGCTTTCT
CCTCAAGGACGCGCCGCCGGCCGATCTGATCTCCGCGGTCCGGGTCGTGGCGGCCGGTGAGGCGCTGCTCGCGCCGTCCG
TGACCCGGCGGCTGATCGCCGATTTCGCCCGCTCGGGGCCGGTGACCCGGAAGGGCCGGCCCTCGCTGCGGCTGAACGGC
CTCACTCCGCGCGAGACGGAGGTCCTGGAGCTGATCGCCCGCGGGCTGTCGAACCAGGAGATCGCCGATGCGCTGATCGT
GGCCGAGCAGACCGTGAAGACCCATGTCAGCCGGGTGCTCGCCAAGTTGGACCTACGGGACCGCGCCCAGGCCGTGATCT
TCGCGTATGAATCGGGGCTGGTCTCGCCCGGTGAGCGGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A640TRR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.892

98.23

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

37.885

100

0.381

Multiple sequence alignment