Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DK181_RS09135 Genome accession   NZ_CP029490
Coordinates   1867057..1867707 (-) Length   216 a.a.
NCBI ID   WP_019770084.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1862057..1872707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS09115 (DK182_09115) - 1863320..1863958 (+) 639 WP_002960285.1 YigZ family protein -
  DK181_RS09120 (DK182_09120) cysK 1864058..1864987 (+) 930 WP_019769631.1 cysteine synthase A -
  DK181_RS09125 (DK182_09125) - 1865206..1865556 (-) 351 WP_002960289.1 S1 RNA-binding domain-containing protein -
  DK181_RS09130 (DK182_09130) - 1865556..1866953 (-) 1398 WP_002960291.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK181_RS09135 (DK182_09135) vraR 1867057..1867707 (-) 651 WP_019770084.1 response regulator Regulator
  DK181_RS09140 (DK182_09140) - 1867685..1868728 (-) 1044 WP_002960295.1 sensor histidine kinase -
  DK181_RS09145 (DK182_09145) liaF 1868725..1869423 (-) 699 WP_002960296.1 cell wall-active antibiotics response protein LiaF -
  DK181_RS09150 (DK182_09150) pknB 1869901..1871766 (-) 1866 WP_002960298.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK181_RS09155 (DK182_09155) - 1871763..1872506 (-) 744 WP_002960300.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24260.91 Da        Isoelectric Point: 4.6313

>NTDB_id=253772 DK181_RS09135 WP_019770084.1 1867057..1867707(-) (vraR) [Streptococcus sobrinus strain SL1]
MKTMDKTKIILVDDHEMVRLGLKSFFNMQPDIEVIGEADNGKDGVEMALELRPDVVVMDLVMPEMDGVEATLAILKEWKA
AKILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVAQGQVAIETEVDQKIKYHDQHPDLHDDLTARERDVLA
LLAKGYDNQTIADELFISLKTVKTHVSNILAKLNVEDRTQAVVYAFQHNLVPQEDQ

Nucleotide


Download         Length: 651 bp        

>NTDB_id=253772 DK181_RS09135 WP_019770084.1 1867057..1867707(-) (vraR) [Streptococcus sobrinus strain SL1]
ATGAAAACGATGGACAAGACTAAAATTATACTGGTTGATGATCATGAAATGGTTCGTCTAGGATTAAAGAGCTTCTTTAA
TATGCAGCCGGACATTGAAGTTATCGGCGAAGCTGATAATGGTAAGGACGGGGTTGAAATGGCACTGGAGCTGAGACCAG
ACGTTGTCGTCATGGACCTGGTCATGCCTGAGATGGATGGAGTTGAAGCCACTCTAGCGATTCTTAAGGAATGGAAGGCT
GCCAAAATTCTGGTTCTGACCTCCTATTTGGATAATGAAAAAATCTACCCTGTCATTGAGGCTGGAGCCAAGGGCTATAT
GCTCAAGACCTCCAGTGCTGCTGAAATTCTCAACAGTATTCGCAAGGTCGCCCAGGGCCAAGTGGCCATTGAAACCGAGG
TTGATCAAAAGATTAAATACCACGATCAGCACCCCGACCTCCACGATGATTTGACAGCCCGAGAACGGGACGTTCTAGCC
CTCTTGGCCAAGGGTTACGACAATCAAACCATCGCCGATGAACTCTTTATTTCGCTCAAGACGGTTAAAACCCATGTTTC
AAACATTTTAGCTAAACTCAATGTTGAAGATCGAACCCAGGCTGTCGTCTATGCCTTCCAGCACAATCTGGTCCCCCAGG
AAGACCAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(151-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.244

94.907

0.477
  degU Bacillus subtilis subsp. subtilis str. 168

36.726

100

0.384