Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DF184_RS02205 Genome accession   NZ_CP029398
Coordinates   430842..431483 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain HN105     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 425842..436483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS02185 (DF184_02185) - 426142..426879 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DF184_RS02190 (DF184_02190) stkP 426879..428873 (+) 1995 WP_044679956.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DF184_RS02195 (DF184_02195) liaF 429198..429857 (+) 660 WP_239425118.1 cell wall-active antibiotics response protein LiaF -
  DF184_RS02200 (DF184_02200) - 429854..430870 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DF184_RS02205 (DF184_02205) vraR 430842..431483 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  DF184_RS02210 (DF184_02210) - 431533..432933 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  DF184_RS02215 (DF184_02215) - 432935..433306 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DF184_RS02220 (DF184_02220) cysK 433332..434258 (-) 927 WP_109371175.1 cysteine synthase A -
  DF184_RS02225 (DF184_02225) - 434348..434980 (-) 633 WP_044769501.1 YigZ family protein -
  DF184_RS02230 (DF184_02230) comFA/cflA 435037..436329 (+) 1293 WP_109371177.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=253148 DF184_RS02205 WP_002937025.1 430842..431483(+) (vraR) [Streptococcus suis strain HN105]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=253148 DF184_RS02205 WP_002937025.1 430842..431483(+) (vraR) [Streptococcus suis strain HN105]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTGGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTAACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCTTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTGAGCGACCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413