Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DF184_RS00355 Genome accession   NZ_CP029398
Coordinates   59231..61168 (+) Length   645 a.a.
NCBI ID   WP_029172056.1    Uniprot ID   -
Organism   Streptococcus suis strain HN105     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 54231..66168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS00335 (DF184_00335) - 55102..56040 (-) 939 WP_024402114.1 IS4 family transposase -
  DF184_RS00340 (DF184_00340) - 56179..57399 (+) 1221 WP_044673318.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  DF184_RS00350 (DF184_00350) - 57590..59113 (+) 1524 WP_044692551.1 quinol oxidase -
  DF184_RS00355 (DF184_00355) hexB 59231..61168 (+) 1938 WP_029172056.1 DNA mismatch repair endonuclease MutL Machinery gene
  DF184_RS00360 (DF184_00360) ruvA 61207..61797 (+) 591 WP_109371013.1 Holliday junction branch migration protein RuvA Machinery gene
  DF184_RS00365 (DF184_00365) - 62162..62731 (+) 570 WP_024398416.1 DNA-3-methyladenine glycosylase I -
  DF184_RS00370 (DF184_00370) cinA 62768..63949 (+) 1182 WP_109371015.1 competence/damage-inducible protein A Machinery gene
  DF184_RS00375 (DF184_00375) recA 64001..65152 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  DF184_RS00380 (DF184_00380) spx 65387..65785 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DF184_RS00385 (DF184_00385) - 65885..66151 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72883.08 Da        Isoelectric Point: 5.1710

>NTDB_id=253122 DF184_RS00355 WP_029172056.1 59231..61168(+) (hexB) [Streptococcus suis strain HN105]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMVIETATADSTHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLKEPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALNLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=253122 DF184_RS00355 WP_029172056.1 59231..61168(+) (hexB) [Streptococcus suis strain HN105]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCGGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGTACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGGTTATTGAGACAGCTACGGCAGACTCTACACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGTATTTATG
GGATTGCGTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCTATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTTAATCGAGC
GATTTTGGAAGGTTATGGTAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGATTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAAAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCCGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCACCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGTAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAACGGGTCAAATACGAATAC
TATCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTAACCTTGTCCACAAAATGGATGCTCTTCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGCATCTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCGATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732