Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B9S64_RS15095 Genome accession   NZ_CP029342
Coordinates   3401016..3401687 (-) Length   223 a.a.
NCBI ID   WP_103492323.1    Uniprot ID   A0A6N9U8U3
Organism   Streptomyces sp. SM18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3396016..3406687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9S64_RS15075 (B9S64_15075) - 3396486..3397028 (-) 543 WP_103492319.1 GbsR/MarR family transcriptional regulator -
  B9S64_RS15080 (B9S64_15080) - 3397122..3398087 (+) 966 WP_103492320.1 ABC transporter ATP-binding protein -
  B9S64_RS15085 (B9S64_15085) - 3398084..3399748 (+) 1665 WP_103492321.1 ABC transporter permease -
  B9S64_RS15090 (B9S64_15090) - 3399784..3400989 (-) 1206 WP_103492322.1 cytochrome P450 -
  B9S64_RS15095 (B9S64_15095) vraR 3401016..3401687 (-) 672 WP_103492323.1 response regulator transcription factor Regulator
  B9S64_RS15100 (B9S64_15100) - 3401684..3403006 (-) 1323 WP_103492324.1 histidine kinase -
  B9S64_RS15105 (B9S64_15105) - 3403126..3404001 (-) 876 WP_103492325.1 S9 family peptidase -
  B9S64_RS15110 (B9S64_15110) kynU 3404130..3405317 (-) 1188 WP_103492326.1 kynureninase -
  B9S64_RS15115 (B9S64_15115) - 3405310..3406158 (-) 849 WP_103492327.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24002.82 Da        Isoelectric Point: 4.8293

>NTDB_id=252852 B9S64_RS15095 WP_103492323.1 3401016..3401687(-) (vraR) [Streptomyces sp. SM18]
MSGSDPIRVLIVDDQMMVREGFSVLLNAMPGIEVVGEAVDGRQAVSQVAALRPDVVLMDIRMPELNGIEATREIVAADAD
AKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLLTEFSKRAEAPRPPAMARIGDL
TERETEVLVLIAQGLSNMEIAAHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=252852 B9S64_RS15095 WP_103492323.1 3401016..3401687(-) (vraR) [Streptomyces sp. SM18]
ATGAGCGGGTCCGACCCCATCCGGGTGCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGATTCTCCGTCCTGCTCAA
CGCGATGCCGGGCATCGAGGTCGTCGGAGAGGCCGTCGACGGCCGGCAGGCCGTGTCACAGGTCGCCGCCCTGCGCCCCG
ACGTGGTGCTGATGGACATCCGGATGCCCGAGCTCAACGGCATCGAGGCGACCCGGGAGATCGTCGCGGCCGACGCCGAC
GCCAAGGTGCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTCTACCAGGCGCTGCGGGCCGGCGCCTCCGGCTTCCT
GCTGAAGGACGCCTCGGCACGCCAACTCGCGGACGGCGTAAGGGTGGTGGCGTCCGGGGAGGCGCTGCTCGCGCCCACCG
TGACCCGGCGACTGCTCACCGAGTTCTCCAAGCGCGCCGAGGCACCCAGGCCGCCCGCCATGGCCCGGATCGGTGACCTG
ACCGAGCGGGAGACGGAGGTGCTCGTGCTGATCGCCCAGGGCCTGTCGAACATGGAGATCGCCGCGCACCTGGTGGTCGC
CGAGTCGACGATCAAGACGCACGTCAGCCGCATCCTGGTGAAGCTGGGCCTGCGGGACCGGACCCAGGCGGCGGTGTTCG
CGTACGAGGCGCGGCTGGTCACCCCCGGATAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-214)

Response regulator receiver domain (Response_reg)

(9-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N9U8U3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.925

95.964

0.422
  degU Bacillus subtilis subsp. subtilis str. 168

42.396

97.309

0.413

Multiple sequence alignment