Detailed information NTG0252847

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: B9S64_RS14200
• Genome accession: NZ_CP029342
• Coordinates: 3200997..3202121 (+)
• Length: 374 a.a.
• NCBI ID: WP_028442179.1
• Uniprot ID: A0A6N9U1H4
• Organism: Streptomyces sp. SM18
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3195997..3207121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9S64_RS14185 (B9S64_14185)	-	3196543..3197382 (+)	840	WP_103490515.1	hypothetical protein	-
B9S64_RS14190 (B9S64_14190)	-	3197473..3199368 (-)	1896	WP_109492053.1	hypothetical protein	-
B9S64_RS14195 (B9S64_14195)	radA/sms	3199504..3200916 (+)	1413	WP_103488682.1	DNA repair protein RadA	Machinery gene
B9S64_RS14200 (B9S64_14200)	disA	3200997..3202121 (+)	1125	WP_028442179.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
B9S64_RS14205 (B9S64_14205)	-	3202314..3203147 (-)	834	WP_258037675.1	hypothetical protein	-
B9S64_RS14210 (B9S64_14210)	-	3203409..3204311 (+)	903	WP_093530867.1	A/G-specific adenine glycosylase	-
B9S64_RS14215 (B9S64_14215)	-	3204511..3205122 (+)	612	WP_103488681.1	SigE family RNA polymerase sigma factor	-
B9S64_RS14220 (B9S64_14220)	-	3205110..3205838 (+)	729	WP_103488680.1	hypothetical protein	-
B9S64_RS14225 (B9S64_14225)	cseB	3205849..3206562 (+)	714	WP_103488679.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40141.94 Da
• Isoelectric Point: 4.8024

>NTDB_id=252847 B9S64_RS14200 WP_028442179.1 3200997..3202121(+) (disA) [Streptomyces sp. SM18]
MAANDRAASPGKSGQGTGNEALMRASLSAVAPGTALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELAKLDGALILDKDMTKILRAGVQLVPDAGIPTEETGTRHRTADRVSKACGFPVVSVSQSMHLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRLIATEIAEYVVELGTDGRLLALQLDELIA
GVDPERELVVRDYVPEPTAKRSRTVAEALDELDTLTHTELLELPVAARALGYSGSPESLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=252847 B9S64_RS14200 WP_028442179.1 3200997..3202121(+) (disA) [Streptomyces sp. SM18]
GTGGCAGCCAACGACCGGGCAGCATCGCCCGGAAAGTCCGGCCAAGGCACGGGGAACGAGGCGCTGATGCGCGCCTCCCT
GAGCGCGGTCGCGCCCGGAACGGCCCTCCGTGACGGCCTGGAGCGCATCCTCCGCGGCAACACCGGAGGCCTGATCGTCC
TCGGCATGGACAAGACCGTCGAGTCCATGTGCACCGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGGCCAAGCTGGACGGCGCCCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTCCC
GGACGCCGGCATCCCCACCGAGGAGACGGGCACCCGTCACCGCACGGCCGACCGCGTCTCCAAGGCGTGCGGGTTCCCCG
TCGTCTCGGTGTCCCAGTCGATGCACCTGATCGCGCTCTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTCTCCCGCGCCAACCAGGCACTCGCCACGCTGGAGCGGTACAAGCTGCGGCTGGACGAGGTCGCCGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTGACGGCGGTCGCCCAGCGCCTGGAGATGGTGCGGCTGATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTTCTGGCCCTCCAGCTGGACGAGTTGATCGCG
GGAGTGGACCCGGAACGCGAGCTGGTCGTCCGCGACTACGTGCCGGAGCCGACCGCCAAGCGGTCGCGCACGGTGGCGGA
GGCGCTGGACGAGCTGGACACGCTCACCCACACCGAGCTGCTGGAACTCCCCGTGGCGGCACGCGCCTTGGGCTACAGCG
GGTCGCCGGAGTCGCTGGACTCGGCGGTGTCACCGAGGGGTTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGAGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTCCTCGCCGCCAGCGTGGACGACCTCCAGGCGGTCGA
CGGGGTCGGCGAGGCCCGCGCGCGCAGCGTGCGGGAGGGACTCTCGCGCCTGGCGGAGTCGTCGATCCTCGAACGGTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A6N9U1H4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433