Detailed information NTG0252569

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DG474_RS08890
• Genome accession: NZ_CP029257
• Coordinates: 1850119..1852653 (-)
• Length: 844 a.a.
• NCBI ID: WP_255778151.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain CCUG 53468
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1845119..1857653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG474_RS08870 (DG474_09015)	-	1846375..1846872 (+)	498	WP_247942982.1	helix-turn-helix domain-containing protein	-
DG474_RS08875 (DG474_09020)	hexB	1847024..1848973 (-)	1950	WP_255778148.1	DNA mismatch repair endonuclease MutL	Machinery gene
DG474_RS08880 (DG474_09025)	-	1849182..1849622 (+)	441	WP_255778149.1	LytTR family DNA-binding domain-containing protein	-
DG474_RS08885 (DG474_09030)	-	1849619..1850077 (+)	459	WP_255778150.1	DUF3021 domain-containing protein	-
DG474_RS08890 (DG474_09035)	hexA	1850119..1852653 (-)	2535	WP_255778151.1	DNA mismatch repair protein MutS	Machinery gene
DG474_RS08895 (DG474_09040)	argR	1852704..1853150 (-)	447	WP_255778152.1	arginine repressor	-
DG474_RS08900 (DG474_09045)	argS	1853305..1854996 (+)	1692	WP_255778153.1	arginine--tRNA ligase	-
DG474_RS08905 (DG474_09050)	-	1855327..1855572 (+)	246	WP_000084865.1	hypothetical protein	-
DG474_RS08910 (DG474_09055)	-	1855771..1857033 (+)	1263	WP_044021502.1	NRAMP family divalent metal transporter	-
DG474_RS08915 (DG474_09060)	nrdI	1857114..1857584 (-)	471	WP_000724244.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94750.21 Da
• Isoelectric Point: 4.8618

>NTDB_id=252569 DG474_RS08890 WP_255778151.1 1850119..1852653(-) (hexA) [Streptococcus oralis strain CCUG 53468]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRVILEGMEQPALAYLIEQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISMLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
EDSQINIQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKDSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGSADKSYGIHVAKIAGLPAELLARADKILTQLESQGQESPTPMRETSA
VTEQMSLFDAPAEHPILAELAKLDVYNMTPIQAMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=252569 DG474_RS08890 WP_255778151.1 1850119..1852653(-) (hexA) [Streptococcus oralis strain CCUG 53468]
ATGGCAACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAGAAACAATACCCAGATGCTTTTTTGCTTTT
TCGAATGGGTGATTTTTACGAGTTGTTCTATGAAGATGCAATTAATGCAGCACAGATTTTAGAAATTTCCTTAACGAGTC
GGAATAAAAATGCAGAAAATCCGATACCCATGGCGGGTGTCCCCTATCATTCTGCCCAGCAGTATATCGATGTTCTGATT
GAGCAGGGCTATAAGGTAGCCATAGCCGAGCAGATGGAAGATCCCAAACAAGCGGTTGGTGTTGTCAAGCGAGAGGTGGT
CCAGGTCATCACACCTGGAACGGTCGTCGATAGCAGTAAGCCGGATAGTCAGAATAATTTCTTGGTTGCCTTAGATCGTG
ATGGCAATCAGTTTGGTCTAGCTTATATGGATTTGGTGACGGGTGATTTCTATGTGACAGGTCTATTAGATTTCACGTTG
GTTTGTGGGGAAATTCGCAACCTCAAGGCGCGAGAAGTAGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGCCGTCAGATGAATTTGGTGCTTTCCTATGAGAAGGAAGGCTTTGAGGACCTTCATTTACTGGATTCACGTTTGGCAG
CTGTGGAGCAAGCAGCAGCTAGTAAGCTCCTCCAGTATGTTCATCGGACCCAGATGCGGGAATTGAACCACCTCAAACCA
GTTATCCGCTATGAAATCAAAGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATGCCCG
TTCAGGTAAGAAGCAGGGGAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGGATGCGTCTCTTGCGTTCTT
GGATTCATCGTCCTTTGATTGATAAGGAGCGAATCGTCCAACGTCAAGAGGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGCAGTGATTTGACAGACAGTCTCAAGGGTGTTTATGATATCGAACGTTTGGCTAGTCGGGTTTCCTTTGGCAAGAC
CAATCCAAAGGATCTCTTGCAATTGGCGACCACTTTATCTAGTGTACCACGGATTCGTGTGATTTTAGAAGGCATGGAGC
AACCTGCCCTGGCCTATCTTATCGAACAGTTAGATGCCATCCCTGAGTTGGAGAGCTTGATTAGCGCTGCCATTGCTCCT
GAAGCTCCTCATGTGATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTAGACAAGTACCGTCGTGTGCT
TAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGGGAAAACTCTGGCATCAGCATGCTCAAGATTGACT
ACAATAAAAAGGACGGCTACTATTTCCATGTGACTAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCAGAACGCTTTGGTACCGAGGAATTAGCTCGTATCGAGGGAGATATGTTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAGTATGAAATCTTTATGCGCATCCGTGAGGAAGTCAGCAAGTACATCCAGCGTTTGCAGGCGCTAGCCC
AAGGAATTGCAACGGTTGATGTCTTGCAAAGTCTCGCAGTTGTGGCTGAAACCCAGCATTTGATCCGACCTGAGTTTGGA
GAGGATTCACAAATCAATATCCAAAAAGGGCGCCATGCTGTCGTCGAAAAGGTCATGGGAGCTCAGACCTATATTCCTAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAGCTGATTACAGGGCCAAACATGAGTGGGAAGTCAACCTACATGCGCC
AGTTAGCCATGACGGCGGTTATGGCCCAGCTGGGTTCTTATGTGCCAGCAGAAAGCGCCCATTTGCCTATCTTCGATGCT
ATCTTTACTCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTCATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACCAAGGATTCCTTGATTCTCTTTGATGAATTGGGACGGGGAACTGCAACTTATGACGGGATGG
CTCTTGCCCAGTCCATCATCGAATATATTCATGAACATATCGGAGCCAAAACCCTCTTTGCGACCCACTACCATGAGTTG
ACCAGTCTGGAGTCTAGCTTGGAACACTTGGTCAATGTCCACGTGGCAACCTTAGAACAGGATGGACAGGTCACCTTCCT
TCACAAGATCGAACCAGGATCAGCTGACAAATCCTATGGTATCCATGTTGCTAAGATTGCTGGCTTACCAGCGGAACTTT
TAGCAAGGGCGGATAAGATTTTAACGCAACTGGAGAGTCAGGGACAAGAAAGCCCAACTCCGATGAGAGAAACAAGTGCT
GTTACTGAACAGATGTCACTCTTTGACGCGCCTGCAGAGCATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTACAA
TATGACACCTATACAGGCTATGAACGTCTTGGTCGAGCTCAAACAAAAGTTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	95.735	100	0.957
mutS	Pseudomonas stutzeri strain ATCC 17587	36.885	100	0.373