Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DG474_RS07955 Genome accession   NZ_CP029257
Coordinates   1639076..1639708 (-) Length   210 a.a.
NCBI ID   WP_084860263.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1634076..1644708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS07940 (DG474_08070) recD/recD2/recDB 1634628..1636997 (+) 2370 WP_255778019.1 ATP-dependent RecD-like DNA helicase Machinery gene
  DG474_RS07945 (DG474_08075) tig 1637045..1638328 (-) 1284 WP_000116504.1 trigger factor -
  DG474_RS07950 (DG474_08080) - 1638419..1639075 (-) 657 WP_084922096.1 DNA alkylation repair protein -
  DG474_RS07955 (DG474_08085) vraR 1639076..1639708 (-) 633 WP_084860263.1 response regulator transcription factor Regulator
  DG474_RS07960 (DG474_08090) - 1639719..1640717 (-) 999 WP_084860264.1 sensor histidine kinase -
  DG474_RS07965 (DG474_08095) liaF 1640714..1641412 (-) 699 WP_255778020.1 cell wall-active antibiotics response protein LiaF -
  DG474_RS07970 (DG474_08100) fni 1641579..1642580 (-) 1002 WP_049520863.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  DG474_RS07975 (DG474_08105) - 1642564..1643571 (-) 1008 WP_000562445.1 phosphomevalonate kinase -
  DG474_RS07980 (DG474_08110) mvaD 1643558..1644511 (-) 954 WP_000375374.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23601.30 Da        Isoelectric Point: 5.1516

>NTDB_id=252553 DG474_RS07955 WP_084860263.1 1639076..1639708(-) (vraR) [Streptococcus oralis strain CCUG 53468]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGIQGISLALKLRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQENF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=252553 DG474_RS07955 WP_084860263.1 1639076..1639708(-) (vraR) [Streptococcus oralis strain CCUG 53468]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGATGATGTAGA
AGTTGTGGGCGAGGCGGCCAACGGTATTCAAGGGATTTCCTTGGCCTTGAAACTGCGTCCAGATGTCATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGACGCGACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATATTAATTGTC
ACCTCTTACTTGGACAATGAAAAAATTATGCCGGTCTTGAATGCGGGTGCCAAAGGTTATATGCTCAAGACTTCTAGTGC
AGACGAACTGCTTCATGCCGTCCGCAAGGTGGCTGCTGGAGAGCTTGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAGCGAGACGTGCTCCAACTCATCGCTAAGGGCTAC
GAAAATCAACGCATTGCAGATGAACTCTTCATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATCCTAGCCAAGCT
TGAGGTCAGTGATCGCACCCAGGCTGCGGTCTATGCCTTTCAGCACCACTTGGTTGGGCAGGAGAACTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41