Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CR542_RS08810 Genome accession   NZ_CP024126
Coordinates   1713352..1714041 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain HA0609     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1708352..1719041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR542_RS08785 (CR542_08765) - 1708822..1709535 (-) 714 WP_099425947.1 nitroreductase family protein -
  CR542_RS08790 (CR542_08770) dnaI 1709532..1710431 (-) 900 WP_002938337.1 primosomal protein DnaI -
  CR542_RS08795 (CR542_08775) - 1710431..1711582 (-) 1152 WP_099425948.1 replication initiation/membrane attachment protein -
  CR542_RS08800 (CR542_08780) nrdR 1711569..1712060 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  CR542_RS08805 (CR542_08785) - 1712132..1713262 (-) 1131 WP_013730514.1 AI-2E family transporter -
  CR542_RS08810 (CR542_08790) covR 1713352..1714041 (-) 690 WP_002942700.1 DNA-binding response regulator Regulator
  CR542_RS08815 (CR542_08795) gndA 1714123..1715550 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  CR542_RS08820 (CR542_08800) - 1715647..1716186 (-) 540 WP_013730515.1 YceD family protein -
  CR542_RS08825 (CR542_08805) trxB 1716196..1717113 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  CR542_RS08830 (CR542_08810) - 1717127..1717351 (-) 225 WP_002936682.1 DUF4059 family protein -
  CR542_RS08835 (CR542_08815) - 1717369..1718712 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=252402 CR542_RS08810 WP_002942700.1 1713352..1714041(-) (covR) [Streptococcus suis strain HA0609]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=252402 CR542_RS08810 WP_002942700.1 1713352..1714041(-) (covR) [Streptococcus suis strain HA0609]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment