Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SAB_RS08185 Genome accession   NC_007622
Coordinates   1653764..1655026 (-) Length   420 a.a.
NCBI ID   WP_000472292.1    Uniprot ID   Q2YTB5
Organism   Staphylococcus aureus RF122     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1648764..1660026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAB_RS08160 (SAB1529c) - 1648962..1649630 (-) 669 WP_000805942.1 uroporphyrinogen-III synthase -
  SAB_RS08165 (SAB1530c) hemC 1649652..1650578 (-) 927 WP_001230219.1 hydroxymethylbilane synthase -
  SAB_RS08170 (SAB1531c) - 1650620..1651435 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  SAB_RS08175 (SAB1532c) hemA 1651457..1652803 (-) 1347 WP_000545448.1 glutamyl-tRNA reductase -
  SAB_RS08180 (SAB1533c) yihA 1653020..1653610 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SAB_RS08185 (SAB1534c) clpX 1653764..1655026 (-) 1263 WP_000472292.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SAB_RS08190 (SAB1535c) tig 1655177..1656478 (-) 1302 WP_000127572.1 trigger factor -
  SAB_RS08195 - 1656526..1656636 (-) 111 WP_001790560.1 hypothetical protein -
  SAB_RS08200 (SAB1536c) - 1656641..1657570 (-) 930 WP_001280013.1 hypothetical protein -
  SAB_RS08205 (SAB1537c) - 1657589..1658197 (-) 609 WP_000032663.1 NUDIX domain-containing protein -
  SAB_RS08215 (SAB1538c) rplT 1658339..1658695 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  SAB_RS08220 (SAB1539c) rpmI 1658742..1658942 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  SAB_RS08225 (SAB1540c) infC 1658971..1659498 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2618

>NTDB_id=25228 SAB_RS08185 WP_000472292.1 1653764..1655026(-) (clpX) [Staphylococcus aureus RF122]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=25228 SAB_RS08185 WP_000472292.1 1653764..1655026(-) (clpX) [Staphylococcus aureus RF122]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGATGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCCATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAAACGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2YTB5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

67.419

95

0.64
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment