Detailed information NTG0251606

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: BXP03_RS05890
• Genome accession: NZ_CP024075
• Coordinates: 1203597..1204397 (-)
• Length: 266 a.a.
• NCBI ID: WP_000835251.1
• Uniprot ID: D7FF31
• Organism: Helicobacter pylori strain 7.13_R2b
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1198597..1209397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BXP03_RS05860 (BXP03_05855)	recJ	1198947..1200497 (+)	1551	WP_000810776.1	single-stranded-DNA-specific exonuclease RecJ	-
BXP03_RS05865 (BXP03_05860)	-	1200497..1201393 (+)	897	WP_001117136.1	RluA family pseudouridine synthase	-
BXP03_RS05870 (BXP03_05865)	-	1201526..1202086 (-)	561	WP_000037134.1	hypothetical protein	-
BXP03_RS05875 (BXP03_05870)	-	1202070..1202408 (-)	339	WP_000699916.1	hypothetical protein	-
BXP03_RS05880 (BXP03_05875)	-	1202596..1203138 (-)	543	WP_000892212.1	tetratricopeptide repeat protein	-
BXP03_RS05885 (BXP03_05880)	dprB	1203196..1203600 (-)	405	WP_000599159.1	Holliday junction resolvase RuvX	Machinery gene
BXP03_RS05890 (BXP03_05885)	dprA	1203597..1204397 (-)	801	WP_000835251.1	DNA-processing protein DprA	Machinery gene
BXP03_RS05895 (BXP03_05890)	minE	1204404..1204637 (-)	234	WP_000051414.1	cell division topological specificity factor MinE	-
BXP03_RS05900 (BXP03_05895)	minD	1204634..1205440 (-)	807	WP_001019050.1	septum site-determining protein MinD	-
BXP03_RS05905 (BXP03_05900)	ilvC	1205464..1206456 (-)	993	WP_001207748.1	ketol-acid reductoisomerase	-
BXP03_RS05915 (BXP03_05910)	-	1206705..1207487 (+)	783	WP_001168242.1	NAD+ synthase	-
BXP03_RS05920 (BXP03_05915)	-	1207484..1208422 (+)	939	WP_000833945.1	tetraacyldisaccharide 4'-kinase	-
BXP03_RS05925 (BXP03_05920)	pseH	1208355..1208897 (-)	543	WP_000742654.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29879.74 Da
• Isoelectric Point: 6.9617

>NTDB_id=251606 BXP03_RS05890 WP_000835251.1 1203597..1204397(-) (dprA) [Helicobacter pylori strain 7.13_R2b]
MKSHFQYSVLENIPKAFDILKDPPKQLYCVGDIKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPTTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMEDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=251606 BXP03_RS05890 WP_000835251.1 1203597..1204397(-) (dprA) [Helicobacter pylori strain 7.13_R2b]
ATGAAAAGCCATTTCCAATACAGCGTACTAGAAAATATCCCTAAAGCCTTTGACATACTCAAAGACCCTCCTAAACAGCT
CTATTGTGTGGGCGATATAAAGCTTTTAGAAGCGCCTTTAAAAGTGGCGATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAACAACGATCATGCTTTCGCCTTGCAGTTTGGATTTTATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTTATGCCCATTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTGTTTGTTTTACCCCAACGCCTGAATGAAAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGGAAGATGAATTTTTAGAATATTGTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (13-197)

3D structure

• AlphaFold DB: D7FF31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	97.368	100	0.974
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414