Detailed information NTG0249836

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: CRD75_RS03540
• Genome accession: NZ_CP023769
• Coordinates: 690951..692180 (+)
• Length: 409 a.a.
• NCBI ID: WP_047298102.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain HarveyGAS
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 685951..697180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRD75_RS03515 (CRD75_03515)	-	686567..687844 (-)	1278	WP_011284699.1	hydroxymethylglutaryl-CoA reductase, degradative	-
CRD75_RS03520 (CRD75_03520)	-	687831..689006 (-)	1176	WP_021340971.1	hydroxymethylglutaryl-CoA synthase	-
CRD75_RS03525 (CRD75_03525)	-	689215..690054 (+)	840	WP_011017679.1	thymidylate synthase	-
CRD75_RS03530 (CRD75_03530)	-	690134..690631 (+)	498	WP_011284701.1	dihydrofolate reductase	-
CRD75_RS03535 (CRD75_03535)	-	690651..690821 (+)	171	WP_002990165.1	hypothetical protein	-
CRD75_RS03540 (CRD75_03540)	clpX	690951..692180 (+)	1230	WP_047298102.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
CRD75_RS03545 (CRD75_03545)	yihA	692190..692789 (+)	600	WP_011284702.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
CRD75_RS03550 (CRD75_03550)	-	692937..693662 (+)	726	Protein_642	hypothetical protein	-
CRD75_RS03555 (CRD75_03555)	-	693737..695836 (-)	2100	WP_011284703.1	ATP-dependent Clp protease ATP-binding subunit	-
CRD75_RS03560 (CRD75_03560)	rpiA	696214..696897 (+)	684	WP_011284704.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45021.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=249836 CRD75_RS03540 WP_047298102.1 690951..692180(+) (clpX) [Streptococcus pyogenes strain HarveyGAS]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFTIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=249836 CRD75_RS03540 WP_047298102.1 690951..692180(+) (clpX) [Streptococcus pyogenes strain HarveyGAS]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTACTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAGCGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572