Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CJ12664_RS06005 Genome accession   NZ_CP028912
Coordinates   1151999..1152664 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain NCTC 12664     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1146999..1157664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJ12664_RS05990 (CJ12664_1157) groES 1148855..1149115 (+) 261 WP_002825273.1 co-chaperone GroES -
  CJ12664_RS05995 (CJ12664_1158) groL 1149136..1150773 (+) 1638 WP_108614569.1 chaperonin GroEL -
  CJ12664_RS06000 (CJ12664_1159) dccS 1150816..1152006 (-) 1191 WP_002868563.1 two-component system sensor histidine kinase DccS -
  CJ12664_RS06005 (CJ12664_1160) ciaR 1151999..1152664 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  CJ12664_RS06010 (CJ12664_1161) - 1152812..1153411 (+) 600 WP_108614570.1 bacteriohemerythrin -
  CJ12664_RS06015 (CJ12664_1162) - 1153422..1153670 (+) 249 WP_002853192.1 ribbon-helix-helix domain-containing protein -
  CJ12664_RS06025 (CJ12664_1164) - 1153928..1155175 (-) 1248 WP_002868562.1 ArsS family sensor histidine kinase -
  CJ12664_RS06030 (CJ12664_1165) - 1155172..1155846 (-) 675 WP_002853196.1 response regulator transcription factor -
  CJ12664_RS06035 (CJ12664_1166) htrA 1155922..1157340 (-) 1419 WP_002873156.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=249262 CJ12664_RS06005 WP_002853205.1 1151999..1152664(-) (ciaR) [Campylobacter jejuni strain NCTC 12664]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=249262 CJ12664_RS06005 WP_002853205.1 1151999..1152664(-) (ciaR) [Campylobacter jejuni strain NCTC 12664]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGTACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362