Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   C1A39_RS07625 Genome accession   NZ_CP028896
Coordinates   1475793..1477892 (-) Length   699 a.a.
NCBI ID   WP_011681535.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS5     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1470793..1482892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1A39_RS07595 (C1A39_07820) pptB 1471250..1472287 (-) 1038 WP_011681529.1 ABC transporter permease Regulator
  C1A39_RS07600 (C1A39_07825) pptA 1472284..1473015 (-) 732 WP_002951673.1 ABC transporter ATP-binding protein Regulator
  C1A39_RS07605 (C1A39_07830) - 1473080..1473499 (+) 420 WP_011681530.1 HIT family protein -
  C1A39_RS07610 (C1A39_07835) - 1473496..1473804 (+) 309 WP_014608635.1 hypothetical protein -
  C1A39_RS07615 (C1A39_07840) - 1473846..1474577 (-) 732 WP_014608636.1 hypothetical protein -
  C1A39_RS07620 (C1A39_07845) - 1474596..1475231 (-) 636 WP_014727665.1 DUF4230 domain-containing protein -
  C1A39_RS10210 - 1475250..1475375 (-) 126 WP_011681534.1 hypothetical protein -
  C1A39_RS07625 (C1A39_07850) clpE 1475793..1477892 (-) 2100 WP_011681535.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  C1A39_RS07630 (C1A39_07855) - 1478608..1479699 (-) 1092 WP_011681536.1 nucleotidyltransferase -
  C1A39_RS07635 (C1A39_07860) - 1479706..1480446 (-) 741 WP_277426406.1 class I SAM-dependent methyltransferase -
  C1A39_RS07640 (C1A39_07870) rsfS 1480771..1481124 (-) 354 WP_011227491.1 ribosome silencing factor -
  C1A39_RS07645 (C1A39_07875) yqeK 1481148..1481738 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  C1A39_RS07650 (C1A39_07880) - 1481735..1482367 (-) 633 WP_002951698.1 nicotinate-nucleotide adenylyltransferase -
  C1A39_RS07655 (C1A39_07885) yhbY 1482471..1482788 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77200.11 Da        Isoelectric Point: 4.8280

>NTDB_id=249062 C1A39_RS07625 WP_011681535.1 1475793..1477892(-) (clpE) [Streptococcus thermophilus strain CS5]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=249062 C1A39_RS07625 WP_011681535.1 1475793..1477892(-) (clpE) [Streptococcus thermophilus strain CS5]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(606-676)

AAA lid domain (AAA_lid_9)

(255-349)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-246)

AAA domain (Cdc48 subfamily) (AAA_2)

(439-599)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.924

100

0.469
  clpC Lactococcus lactis subsp. cremoris KW2

49.219

91.559

0.451
  clpE Streptococcus pneumoniae D39

48.657

90.558

0.441
  clpE Streptococcus pneumoniae R6

48.657

90.558

0.441
  clpE Streptococcus pneumoniae Rx1

48.657

90.558

0.441
  clpE Streptococcus pneumoniae TIGR4

48.657

90.558

0.441
  clpC Bacillus subtilis subsp. subtilis str. 168

45.975

92.418

0.425
  clpC Streptococcus thermophilus LMD-9

43.26

91.273

0.395
  clpC Streptococcus thermophilus LMG 18311

43.103

91.273

0.393
  clpC Streptococcus pneumoniae TIGR4

43.499

89.127

0.388
  clpC Streptococcus pneumoniae Rx1

43.499

89.127

0.388
  clpC Streptococcus pneumoniae D39

43.499

89.127

0.388
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.598

88.269

0.385
  clpC Streptococcus mutans UA159

43.156

88.841

0.383

Multiple sequence alignment