Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DBP13_RS19975 Genome accession   NZ_CP028834
Coordinates   4330770..4331435 (+) Length   221 a.a.
NCBI ID   WP_128802486.1    Uniprot ID   -
Organism   Streptomyces sp. M2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4325770..4336435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DBP13_RS19955 kynU 4326542..4327759 (+) 1218 WP_128802483.1 kynureninase -
  DBP13_RS19960 - 4327696..4328106 (-) 411 WP_128802484.1 hypothetical protein -
  DBP13_RS19965 - 4328375..4329262 (+) 888 WP_108010737.1 alpha/beta hydrolase -
  DBP13_RS19970 - 4329361..4330788 (+) 1428 WP_128802485.1 histidine kinase -
  DBP13_RS19975 vraR 4330770..4331435 (+) 666 WP_128802486.1 response regulator transcription factor Regulator
  DBP13_RS19980 - 4331455..4332675 (+) 1221 WP_128802487.1 cytochrome P450 -
  DBP13_RS19985 - 4332772..4333359 (+) 588 WP_108011109.1 Uma2 family endonuclease -
  DBP13_RS19990 - 4333370..4335004 (-) 1635 WP_128802488.1 ABC transporter permease -
  DBP13_RS19995 - 4335001..4335915 (-) 915 WP_108010756.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23852.56 Da        Isoelectric Point: 4.7428

>NTDB_id=248489 DBP13_RS19975 WP_128802486.1 4330770..4331435(+) (vraR) [Streptomyces sp. M2]
MAIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVDRVRELAPDVVLMDIRMPELNGIEATREIVAADTTAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTRRLITEFSKLAEAPRHLASAQAAYGDLTE
RETEVLVLIAQGLSNAEIAGRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=248489 DBP13_RS19975 WP_128802486.1 4330770..4331435(+) (vraR) [Streptomyces sp. M2]
ATGGCCATCCGCGTCCTGATCGCGGACGATCAGATGATGGTGCGTGAGGGCTTCTCCGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCCGTCAACGGGCGCGAGGCGGTCGACCGGGTCCGCGAACTCGCCCCCGACGTCGTCCTGA
TGGACATCCGTATGCCCGAGCTGAACGGCATCGAGGCGACCAGGGAGATCGTGGCGGCCGACACCACCGCCAAGGTCCTG
GTCCTGACGACCTTCGACCTCGACGAGTACGTGTACCAGGCCCTGCGCGCGGGCGCCTCCGGCTTCCTCCTCAAGGACGC
CTCCGCCCGCCAACTCGCGGACGGCGTACGGGTGGTGGCAGCGGGCGAGGCCCTCCTCGCACCGACCGTGACGAGGCGCC
TGATCACGGAGTTCTCGAAACTGGCGGAAGCACCGCGCCACCTGGCGTCCGCCCAGGCGGCCTACGGCGACCTGACCGAA
CGCGAGACCGAGGTCCTCGTCCTCATCGCCCAGGGCCTGTCCAACGCCGAGATCGCCGGCCGCCTGGTCGTGGCCGAGTC
CACGATCAAAACCCACGTCAGCCGCATCCTGGTCAAGCTGGGCCTGCGCGACCGCACCCAGGCGGCGGTGTTCGCGTACG
AGGCGAGGCTGGTCACGCCGGGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.495

98.643

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

42.396

98.19

0.416