Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CPC18_RS04315 Genome accession   NZ_CP023561
Coordinates   865243..865812 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TF3198     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 860243..870812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CPC18_RS04290 (CPC18_04275) cysE 861456..862103 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CPC18_RS04295 (CPC18_04280) cysS 862087..863487 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  CPC18_RS04300 (CPC18_04285) - 863480..863884 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CPC18_RS04305 (CPC18_04290) rlmB 863892..864638 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CPC18_RS04310 (CPC18_04295) - 864638..865162 (+) 525 WP_000664738.1 NYN domain-containing protein -
  CPC18_RS04315 (CPC18_04300) sigH 865243..865812 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  CPC18_RS04320 (CPC18_04305) rpmG 865927..866070 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CPC18_RS04325 (CPC18_04310) secE 866126..866308 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CPC18_RS04330 (CPC18_04315) nusG 866321..866869 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CPC18_RS04335 (CPC18_04320) rplK 867050..867472 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  CPC18_RS04340 (CPC18_04325) rplA 867680..868372 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CPC18_RS04350 (CPC18_04335) rplJ 868644..869144 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  CPC18_RS04355 (CPC18_04340) rplL 869187..869555 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CPC18_RS04360 (CPC18_04345) - 869730..870338 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=248410 CPC18_RS04315 WP_000872873.1 865243..865812(+) (sigH) [Staphylococcus aureus strain TF3198]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=248410 CPC18_RS04315 WP_000872873.1 865243..865812(+) (sigH) [Staphylococcus aureus strain TF3198]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment