Detailed information NTG0247997

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: CO687_RS10255
• Genome accession: NZ_CP023511
• Coordinates: 2077820..2080081 (+)
• Length: 753 a.a.
• NCBI ID: WP_096755381.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_371
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2072820..2085081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO687_RS10220 (CO687_10220)	-	2072944..2073156 (-)	213	WP_008809086.1	exodeoxyribonuclease VII small subunit	-
CO687_RS10225 (CO687_10225)	xseA	2073134..2074474 (-)	1341	WP_096755378.1	exodeoxyribonuclease VII large subunit	-
CO687_RS10235 (CO687_10235)	-	2074630..2075472 (-)	843	WP_096755379.1	NAD(P)H-hydrate dehydratase	-
CO687_RS10240 (CO687_10240)	-	2075580..2076353 (-)	774	WP_096755380.1	HAD hydrolase family protein	-
CO687_RS10245 (CO687_10245)	-	2076350..2077204 (-)	855	WP_045773845.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
CO687_RS10250 (CO687_10250)	-	2077337..2077567 (-)	231	WP_008809091.1	DUF1797 family protein	-
CO687_RS10255 (CO687_10255)	clpE	2077820..2080081 (+)	2262	WP_096755381.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
CO687_RS10260 (CO687_10260)	-	2080132..2080737 (-)	606	WP_096755382.1	GyrI-like domain-containing protein	-
CO687_RS10265 (CO687_10265)	-	2080797..2081687 (-)	891	WP_096755383.1	YafY family protein	-
CO687_RS10270 (CO687_10270)	-	2081847..2082299 (+)	453	WP_096755384.1	NUDIX hydrolase	-
CO687_RS10275 (CO687_10275)	-	2082398..2082697 (+)	300	WP_045773849.1	DUF1827 family protein	-
CO687_RS10280 (CO687_10280)	-	2082734..2083171 (-)	438	WP_096755385.1	GNAT family N-acetyltransferase	-
CO687_RS10285 (CO687_10285)	-	2083194..2083649 (+)	456	WP_096755386.1	MarR family transcriptional regulator	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83928.00 Da
• Isoelectric Point: 5.0233

>NTDB_id=247997 CO687_RS10255 WP_096755381.1 2077820..2080081(+) (clpE) [Streptococcus gordonii strain FDAARGOS_371]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLLSGLTNMNNHNMDPFDDFFNHLGNFQGPKDSTPPTQ
SGGSYGGGNYGPGSNNQHPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDSDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQNA
KMDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNEIHLDVTAKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKKKAELDQTTDISTSSD

Nucleotide

• Length: 2262 bp

>NTDB_id=247997 CO687_RS10255 WP_096755381.1 2077820..2080081(+) (clpE) [Streptococcus gordonii strain FDAARGOS_371]
ATGCTTTGTCAAAACTGTAAAATTAATGAATCTACCATTCATTTATACACTAATGTAAATGGTAAAAAACAACAAGTCGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACTGATCCAAATAACTCTCTTTTGAGTGGACTGACGAACATGAACAATC
ATAATATGGATCCTTTTGATGATTTCTTTAATCATCTGGGGAATTTCCAAGGGCCGAAGGATTCTACCCCTCCAACTCAG
TCAGGTGGTAGTTACGGAGGGGGCAACTATGGTCCTGGTTCTAACAACCAGCATCCTCAGTCAGCTTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGCATTAACGTTACAGAAATTGCTCGACGTGGTGATATTGATCCAGTGATTGGACGAGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAATAATCCAGTCCTTATTGGCGAACCTGGTGTCGGC
AAGACTGCTGTTGTAGAGGGCTTGGCACAGAAAATAGTCGATAGTGATGTTCCTCAAAAACTGCAAGGAAAAGAGGTCAT
TCGACTTGATGTTGTGAGCCTTGTTCAAGGAACTGGTATTCGTGGACAATTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGATATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGCTCTGCGGGGGATGGG
AACATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTCGGAGCTACTACTCTCAATGA
ATATCGTATCATTGAAAAAGATGCAGCTTTAGAAAGACGGATGCAACCAGTCAAAGTAGATGAACCAACTGTAGAAGAAA
CGATCACAATTCTAAAGGGAATTCAAAAGAAATACGAAGATTACCACCATGTTCGCTACACAGATGAGGCTATTGAAGCT
GCAGCCATCCTATCTAATCGTTATATTCAGGACCGTTTCCTTCCTGATAAAGCTATCGATCTTTTGGATGAATCAGGCTC
TAAGATGAACCTAACCCTCAATTTTGTCGATCCAAAAGAAATTGACAGACGCTTGATAGAGGCTGAAAATCTGAAAACAC
AGGCCACTCGCGATGAAGATTACGAAAAAGCAGCCTACTTCCGCGACCAAATTGCCAAATATAAGGAAATGCAAAATGCT
AAAATGGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAAGCTATTGTCGAGCAAAAAACAAATATTCCTGT
TGGTGATTTGAAGGAAAAAGAGCAGTCTCAGCTTATTCATTTAGCTAGTGATTTGAAGTCTCATGTCATTGGGCAGGATG
ATGCTGTTGATAAGATTGCAAAAGCCATCCGTCGTAATCGTGTGGGATTAGGCAGTCCAAACCGGCCAATCGGAAGTTTC
CTTTTTGTTGGACCGACAGGCGTTGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGCTCTGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGCGTTGCCAAACTTGTAGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGCCAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCTTAGACGAAGTAGAAAAA
GCCCATCCAGATGTCATGCATATGTTCTTACAAGTCTTAGATGACGGACGTTTGACTGATGGACAAGGTCGAACAGTCAG
CTTCAAAGATACCATTATCATTATGACTTCCAATGCAGGAACCGGTAAAGTGGAAGCAAGCGTTGGTTTTGGAGCCGCCC
GAGAAGGTCGAACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAACCGATTTGATGGTATT
ATTGAATTCAAGGCATTAAGCAAGGACAATCTCTTACAAATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTTGC
TAGCAACGAAATTCATCTAGATGTAACAGCTAAAGTCAAAGAAAAATTGGTTGATCTGGGCTACGATCCTAAGATGGGGG
CACGACCACTCCGCAGAACCATTCAGGACCATATCGAAGATGCTATTACGGACTACTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATTATGACTAGCAATGGCAAGATTATAATTAAGGGGAAAAAGAAAGCTGAGCTTGATCAAACAACCGA
CATCAGCACAAGCTCAGATTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (646-718)

• AAA domain (Cdc48 subfamily) (AAA_2) (475-638)

• AAA lid domain (AAA_lid_9) (290-387)

• ATPase family associated with various cellular activities (AAA) (AAA) (152-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.729	99.07	0.859
clpE	Streptococcus pneumoniae D39	86.729	99.07	0.859
clpE	Streptococcus pneumoniae R6	86.729	99.07	0.859
clpE	Streptococcus pneumoniae TIGR4	86.595	99.07	0.858
clpE	Streptococcus mutans UA159	85.121	99.07	0.843
clpC	Lactococcus lactis subsp. cremoris KW2	77.321	100	0.774
clpC	Bacillus subtilis subsp. subtilis str. 168	50.592	89.774	0.454
clpC	Streptococcus pneumoniae Rx1	47.84	83.001	0.397
clpC	Streptococcus pneumoniae D39	47.84	83.001	0.397
clpC	Streptococcus pneumoniae TIGR4	47.68	83.001	0.396
clpC	Streptococcus thermophilus LMD-9	44.985	87.384	0.393
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.603	84.064	0.392
clpC	Streptococcus thermophilus LMG 18311	44.681	87.384	0.39
clpC	Streptococcus mutans UA159	47.343	82.47	0.39