Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   CO687_RS07995 Genome accession   NZ_CP023511
Coordinates   1619065..1620294 (+) Length   409 a.a.
NCBI ID   WP_096755239.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1605118..1624353 1619065..1620294 within 0


Gene organization within MGE regions


Location: 1605118..1624353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS07910 (CO687_07910) guaC 1605118..1606101 (+) 984 WP_008808651.1 GMP reductase -
  CO687_RS07915 (CO687_07915) - 1606282..1606863 (+) 582 WP_008808652.1 xanthine phosphoribosyltransferase -
  CO687_RS07920 (CO687_07920) - 1606865..1608130 (+) 1266 WP_037622361.1 nucleobase:cation symporter-2 family protein -
  CO687_RS07925 (CO687_07925) - 1608244..1608426 (-) 183 WP_001117401.1 4-oxalocrotonate tautomerase -
  CO687_RS07930 (CO687_07930) - 1608548..1609123 (+) 576 WP_008808654.1 thymidine kinase -
  CO687_RS07935 (CO687_07935) prfA 1609156..1610235 (+) 1080 WP_048775986.1 peptide chain release factor 1 -
  CO687_RS07940 (CO687_07940) prmC 1610235..1611065 (+) 831 WP_060970602.1 peptide chain release factor N(5)-glutamine methyltransferase -
  CO687_RS07945 (CO687_07945) - 1611058..1611648 (+) 591 WP_060970603.1 L-threonylcarbamoyladenylate synthase -
  CO687_RS07950 (CO687_07950) glyA 1611696..1612958 (+) 1263 WP_060970604.1 serine hydroxymethyltransferase -
  CO687_RS07955 (CO687_07955) - 1612960..1613934 (+) 975 WP_060970605.1 nucleoid-associated protein -
  CO687_RS07960 (CO687_07960) - 1613934..1614536 (+) 603 WP_048779992.1 lysozyme family protein -
  CO687_RS07965 (CO687_07965) - 1614647..1615492 (+) 846 WP_096755234.1 alpha/beta hydrolase -
  CO687_RS07970 (CO687_07970) - 1615668..1616627 (+) 960 WP_096755235.1 ROK family glucokinase -
  CO687_RS07975 (CO687_07975) - 1616726..1617565 (+) 840 WP_096755236.1 thymidylate synthase -
  CO687_RS07980 (CO687_07980) - 1617697..1618191 (+) 495 WP_096755237.1 hypothetical protein -
  CO687_RS07985 (CO687_07985) - 1618344..1618856 (+) 513 WP_096755238.1 dihydrofolate reductase -
  CO687_RS07995 (CO687_07995) clpX 1619065..1620294 (+) 1230 WP_096755239.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  CO687_RS08000 (CO687_08000) yihA 1620304..1620897 (+) 594 WP_045774030.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  CO687_RS08005 (CO687_08005) - 1621031..1621720 (+) 690 WP_012000547.1 glucosaminidase domain-containing protein -
  CO687_RS08010 (CO687_08010) - 1621848..1622645 (+) 798 WP_096755240.1 formate/nitrite transporter family protein -
  CO687_RS08015 (CO687_08015) - 1622739..1623563 (+) 825 WP_045774027.1 alpha/beta hydrolase -
  CO687_RS08020 (CO687_08020) - 1623613..1624353 (+) 741 WP_096755430.1 alpha/beta hydrolase-fold protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45678.23 Da        Isoelectric Point: 4.4870

>NTDB_id=247988 CO687_RS07995 WP_096755239.1 1619065..1620294(+) (clpX) [Streptococcus gordonii strain FDAARGOS_371]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTR
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=247988 CO687_RS07995 WP_096755239.1 1619065..1620294(+) (clpX) [Streptococcus gordonii strain FDAARGOS_371]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTCTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGCCAAGAGCGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGCATTAATTTTCACGATAGTCGTGAAGAAGATGATGT
TGAATTGCAAAAATCAAATATCTTAATGATTGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAAACCTTGGCTAGAA
GTTTAAATGTGCCTTTTGCGATTGCTGATGCGACAGCATTAACAGAGGCTGGTTATGTCGGAGAAGATGTAGAAAATATT
CTTTTAAAACTTTTACAGGCGGCTGACTTCAATATTGAACGTGCAGAACGCGGAATTATCTACGTTGATGAGATTGATAA
GATCGCTAAAAAAAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCTCTCTTAAAAATTA
TTGAAGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAGCATCCGCAGCAAGAAATGATTCAAGTTGATACCAGG
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGAATTGAAGAAATTGTTAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAGGCTATTATTGCCGAAGATATTCAAAAATTTG
GAATTATCCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTAGTTCGTATT
CTTCGTGAGCCAAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTATGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATCGAGCGCAAAACTGGGGCTCGCGGTCTACGTTCTATCATAGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCCGAATTACTAAAGAAGCTGTTGATGGT
ACGGATAAGCCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.33

100

0.853
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment