Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CO687_RS00630 Genome accession   NZ_CP023511
Coordinates   119441..120130 (-) Length   229 a.a.
NCBI ID   WP_012000010.1    Uniprot ID   A0AAP2NYS9
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 114441..125130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS00610 (CO687_00610) nrdR 114845..115318 (-) 474 WP_012000014.1 transcriptional regulator NrdR -
  CO687_RS00615 (CO687_00615) - 115498..115899 (+) 402 Protein_107 hypothetical protein -
  CO687_RS00620 (CO687_00620) - 116056..116871 (-) 816 WP_096754723.1 endonuclease/exonuclease/phosphatase family protein -
  CO687_RS00625 (CO687_00625) - 116889..119081 (-) 2193 WP_061599623.1 PTS transporter subunit IIBC -
  CO687_RS00630 (CO687_00630) covR 119441..120130 (-) 690 WP_012000010.1 response regulator transcription factor Regulator
  CO687_RS00635 (CO687_00635) gndA 120143..121567 (-) 1425 WP_096754724.1 NADP-dependent phosphogluconate dehydrogenase -
  CO687_RS00640 (CO687_00640) - 121703..123184 (-) 1482 WP_012000008.1 flotillin family protein -
  CO687_RS00645 (CO687_00645) - 123286..123816 (-) 531 WP_045505786.1 DUF177 domain-containing protein -
  CO687_RS00650 (CO687_00650) - 123915..124784 (+) 870 WP_061596098.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26261.28 Da        Isoelectric Point: 5.1919

>NTDB_id=247936 CO687_RS00630 WP_012000010.1 119441..120130(-) (covR) [Streptococcus gordonii strain FDAARGOS_371]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSQLKVPTAYRNLRVDLKNHTVYRGEEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=247936 CO687_RS00630 WP_012000010.1 119441..120130(-) (covR) [Streptococcus gordonii strain FDAARGOS_371]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTCATCATGTTGGAATTACAAAAAGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGACAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGCTGCAGTTATCATTGTAATG
GTGAGTCGGGAGGAAATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATCTGGTTGATAAAATTTCTGCTATTTTTCGTGGACGAGATTTTATTGATCAGAAATGTAGCCAGTTAAAAGTTC
CTACCGCTTATCGTAATCTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGAAGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGACCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACCAATATAGTGGATGTATATATTCGTTACCTCCGCAGTAAAATCGATCTTCCTGGACAAG
AAAGTTATATTAAAACTGTTCGTGGAATTGGTTATTCCATGCAGGGTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment