Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CO686_RS07570 Genome accession   NZ_CP023507
Coordinates   1525508..1526197 (-) Length   229 a.a.
NCBI ID   WP_000518005.1    Uniprot ID   A0A1X0WQD0
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1520508..1531197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS07550 (CO686_07550) - 1521482..1522489 (-) 1008 WP_000562391.1 phosphomevalonate kinase -
  CO686_RS07555 (CO686_07555) mvaD 1522476..1523429 (-) 954 WP_096753683.1 diphosphomevalonate decarboxylase -
  CO686_RS07560 (CO686_07560) mvk 1523411..1524289 (-) 879 WP_000163295.1 mevalonate kinase -
  CO686_RS07565 (CO686_07565) cbpJ 1524407..1525408 (-) 1002 WP_096753684.1 choline-binding protein CbpJ -
  CO686_RS07570 (CO686_07570) covR 1525508..1526197 (-) 690 WP_000518005.1 response regulator transcription factor Regulator
  CO686_RS07575 (CO686_07575) gndA 1526209..1527633 (-) 1425 WP_000158773.1 NADP-dependent phosphogluconate dehydrogenase -
  CO686_RS07580 (CO686_07580) - 1527709..1529154 (-) 1446 WP_096753685.1 cell division site-positioning protein MapZ family protein -
  CO686_RS07585 (CO686_07585) - 1529167..1530324 (-) 1158 WP_096753686.1 class I SAM-dependent RNA methyltransferase -
  CO686_RS07595 (CO686_07595) gpsB 1530810..1531139 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26827.00 Da        Isoelectric Point: 8.0271

>NTDB_id=247871 CO686_RS07570 WP_000518005.1 1525508..1526197(-) (covR) [Streptococcus oralis strain FDAARGOS_367]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=247871 CO686_RS07570 WP_000518005.1 1525508..1526197(-) (covR) [Streptococcus oralis strain FDAARGOS_367]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACATTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X0WQD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment