Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   CO686_RS02370 Genome accession   NZ_CP023507
Coordinates   455911..457143 (+) Length   410 a.a.
NCBI ID   WP_002874765.1    Uniprot ID   A0A1X1GRP7
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 450911..462143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS02335 (CO686_02335) galE 451583..452602 (+) 1020 WP_001156532.1 UDP-glucose 4-epimerase GalE -
  CO686_RS02340 (CO686_02340) - 452604..453569 (+) 966 WP_049500670.1 glycosyltransferase family 2 protein -
  CO686_RS02345 (CO686_02345) - 453645..453848 (-) 204 WP_002874767.1 ferredoxin -
  CO686_RS02350 (CO686_02350) - 453894..454400 (+) 507 WP_049549902.1 SAG1386/EF1546 family surface-associated protein -
  CO686_RS02355 (CO686_02355) cmk 454410..455084 (+) 675 WP_049549903.1 (d)CMP kinase -
  CO686_RS02360 (CO686_02360) - 455203..455709 (+) 507 WP_049489755.1 dihydrofolate reductase -
  CO686_RS02365 (CO686_02365) - 455709..455879 (+) 171 WP_000442252.1 hypothetical protein -
  CO686_RS02370 (CO686_02370) clpX 455911..457143 (+) 1233 WP_002874765.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  CO686_RS02375 (CO686_02375) yihA 457152..457739 (+) 588 WP_000405203.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  CO686_RS02380 (CO686_02380) - 457749..458129 (+) 381 WP_001140428.1 RidA family protein -
  CO686_RS02385 (CO686_02385) rapZ 458181..459071 (+) 891 WP_000163039.1 RNase adapter RapZ -
  CO686_RS02390 (CO686_02390) - 459068..460045 (+) 978 WP_049500661.1 YvcK family protein -
  CO686_RS02395 (CO686_02395) whiA 460042..460953 (+) 912 WP_049500659.1 DNA-binding protein WhiA -
  CO686_RS02400 (CO686_02400) - 460986..461954 (-) 969 WP_049500657.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45686.26 Da        Isoelectric Point: 4.4581

>NTDB_id=247848 CO686_RS02370 WP_002874765.1 455911..457143(+) (clpX) [Streptococcus oralis strain FDAARGOS_367]
MPTNRKNDMMVYCSFCGKSQEEVKKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTEKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=247848 CO686_RS02370 WP_002874765.1 455911..457143(+) (clpX) [Streptococcus oralis strain FDAARGOS_367]
ATGCCTACAAATAGGAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTAAAGAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTGGAGTTGGCCCAGGAAATCATTCGGGAGGAGTTGGCTGAGGAAG
TCTTGGCAGACTTGTCTGAAGTACCAAAACCAATCGAACTCCTCAATATCCTAAACCACTATGTGATTGGTCAGGATCGT
GCCAAACGTGCCTTGGCAGTGGCAGTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCTGGGAAAACCTTCTTGGCTCAGACTTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCAGATGCGACAGCTCTGACTGAGGCTGGGTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGCTGCTGACTTTAACATCGAACGTGCAGAACGTGGGATTATCTACGTAGATGAAATTGA
CAAAATTGCCAAGAAGAGCGAGAATGTGTCTATCACACGTGACGTTTCGGGCGAAGGGGTACAACAAGCCCTTCTCAAGA
TTATCGAGGGAACCGTTGCTAGCGTACCGCCTCAAGGAGGACGCAAACATCCACAACAAGAGATGATTCAGGTGGATACT
AAAAATATCCTCTTTATCGTGGGTGGTGCTTTTGATGGCATCGAAGAAATTGTCAAACAACGTTTGGGTGAAAAGGTTAT
TGGATTTGGTCAAAATAATAAGGCGATTGACGAAAATAGCTCCTACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TCGGGATTATTCCTGAGTTGATTGGACGTTTGCCAGTCTTTGCAGCTCTTGAGCAATTAACAGTCGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAATACCAAACCTTGCTTTCTTATGACGATGTCGAGTTGGAATTTGA
CGACGAAGCTCTTCAAGAGATTGCCAATAAGGCTATCGAACGCAAAACGGGTGCGCGTGGTCTTCGCTCCATCATCGAAG
AAACCATGCTAGACGTTATGTTTGAAGTGCCAAGTCAGGAAAATGTGAAATTGGTCCGCATCACCAAAGAAGCTGTTGAC
GGAACGGAAAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GRP7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.073

100

0.871
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment