Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AOY64_RS09140 Genome accession   NZ_CP028763
Coordinates   1925437..1926093 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain A11     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1920437..1931093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY64_RS09110 (AOY64_09685) dcyD 1921317..1922303 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  AOY64_RS09115 (AOY64_09690) tcyL 1922318..1922986 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AOY64_RS09120 (AOY64_09695) tcyN 1922983..1923735 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AOY64_RS09125 (AOY64_09700) sdiA 1923965..1924687 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  AOY64_RS09130 (AOY64_09705) yecF 1924754..1924978 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AOY64_RS09135 yecU 1924965..1925141 (-) 177 WP_000590347.1 protein YecU -
  AOY64_RS23060 - 1925224..1925295 (-) 72 Protein_1792 transcriptional regulator -
  AOY64_RS09140 (AOY64_09710) letA 1925437..1926093 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AOY64_RS09145 (AOY64_09715) uvrC 1926090..1927922 (+) 1833 WP_087894948.1 excinuclease ABC subunit UvrC Machinery gene
  AOY64_RS09150 (AOY64_09720) pgsA 1927979..1928527 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AOY64_RS09170 (AOY64_09740) yecA 1929177..1929842 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=247753 AOY64_RS09140 WP_000611335.1 1925437..1926093(+) (letA) [Escherichia coli strain A11]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=247753 AOY64_RS09140 WP_000611335.1 1925437..1926093(+) (letA) [Escherichia coli strain A11]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment