Detailed information NTG0247705

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CO689_RS01730
• Genome accession: NZ_CP023497
• Coordinates: 157025..158068 (-)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain FDAARGOS_383
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 152025..163068

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO689_RS01700 (CO689_01700)	-	153149..153355 (-)	207	WP_002481657.1	DUF1128 family protein	-
CO689_RS01705 (CO689_01705)	-	153579..154043 (+)	465	WP_002481658.1	low molecular weight protein-tyrosine-phosphatase	-
CO689_RS01710 (CO689_01710)	-	154051..154341 (+)	291	WP_002481659.1	hypothetical protein	-
CO689_RS01715 (CO689_01715)	-	154472..155548 (+)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
CO689_RS01720 (CO689_01720)	-	155757..156335 (+)	579	WP_002481661.1	carbonic anhydrase	-
CO689_RS01725 (CO689_01725)	vraR	156406..157035 (-)	630	WP_002481662.1	response regulator transcription factor	Regulator
CO689_RS01730 (CO689_01730)	vraS	157025..158068 (-)	1044	WP_002481663.1	sensor histidine kinase	Regulator
CO689_RS01735 (CO689_01735)	liaF	158065..158766 (-)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
CO689_RS01740 (CO689_01740)	-	158782..159177 (-)	396	WP_002481665.1	hypothetical protein	-
CO689_RS01745 (CO689_01745)	map	159293..160057 (-)	765	WP_002481666.1	type I methionyl aminopeptidase	-
CO689_RS01750 (CO689_01750)	-	160277..161263 (+)	987	WP_002481667.1	aromatic acid exporter family protein	-
CO689_RS01755 (CO689_01755)	-	161346..162065 (-)	720	WP_002481668.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=247705 CO689_RS01730 WP_002481663.1 157025..158068(-) (vraS) [Staphylococcus simulans strain FDAARGOS_383]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=247705 CO689_RS01730 WP_002481663.1 157025..158068(-) (vraS) [Staphylococcus simulans strain FDAARGOS_383]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAGTTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGAGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862